News tagged with glycogen
Glycogen
Glycogen is a molecule that serves as the secondary long-term energy storage in animal and fungal cells, with the primary energy stores being held in adipose tissue. Glycogen is made primarily by the liver and the muscles, but can also be made by glycogenesis within the brain and stomach.
Glycogen is the analogue of starch, a glucose polymer in plants, and is sometimes referred to as animal starch, having a similar structure to amylopectin but more extensively branched and compact than starch. Glycogen is a polymer of α(1→4) glycosidic bonds linked, with α(1→6)-linked branches. Glycogen is found in the form of granules in the cytosol/cytoplasm in many cell types, and plays an important role in the glucose cycle. Glycogen forms an energy reserve that can be quickly mobilized to meet a sudden need for glucose, but one that is less compact than the energy reserves of triglycerides (lipids).
In the liver hepatocytes, glycogen can compose up to eight percent of the fresh weight (100–120 g in an adult) soon after a meal. Only the glycogen stored in the liver can be made accessible to other organs. In the muscles, glycogen is found in a low concentration (one to two percent of the muscle mass). However, the amount of glycogen stored in the body—especially within the muscles, liver, and red blood cells—mostly depends on physical training, basal metabolic rate, and eating habits such as intermittent fasting. Small amounts of glycogen are found in the kidneys, and even smaller amounts in certain glial cells in the brain and white blood cells. The uterus also stores glycogen during pregnancy to nourish the embryo.
For more information about Glycogen, read the full article at
Wikipedia.
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Separating a cancer prevention drug from heart disease risk
Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. But what if this ...
Sep 13, 2011 |
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Mouse model brings new perspectives on Lafora disease
Short-term energy storage in animal cells is usually achieved through the accumulation of glucose, in the form of long and branched chains, known as glycogen. But when this accumulation happens in neurons it is fatal, causing ...
Aug 29, 2011 |
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Liver structure could hold the key to battling diabetes
(Medical Xpress) -- Our liver could be a major springboard for determining life-changing diabetes diagnosis and treatment thanks to a world-first discovery by an Australian-Chinese research team.
Jun 15, 2011 |
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Answers to a rare and tragic form of epilepsy
A new study offers critical insight into the biochemistry of a rare and fatal form of epilepsy known as Lafora disease, a genetic condition that typically strikes children in their teens. The disease is characterized ...
Mar 01, 2011 |
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Gut bacteria can control organ functions
Bacteria in the human gut may not just be helping digest food but also could be exerting some level of control over the metabolic functions of other organs, like the liver, according to research published this week in the ...
Feb 28, 2011 |
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Scientists discover key to Christmas Island's red crab migration
One of the most spectacular migrations on Earth is that of the Christmas Island red crab (Gecarcoidea natalis). Acknowledged as one of the wonders of the natural world, every year millions of the crabs simultaneously ...
Aug 27, 2010 |
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Mayo researchers find obesity key
Mayo researchers collaborating with investigators at the University of Iowa, University of Connecticut and New York University (NYU) have discovered a molecular mechanism that controls energy expenditure in muscles and helps ...
Jan 05, 2010 |
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An often overlooked protein actually a potent regulator of cardiac hypertrophy
A protein long thought to be a secondary regulator in the heart's response to stressors like hypertension actually appears to be a primary regulator according to researchers from the Center for Translational Medicine at Thomas ...
Nov 16, 2009 |
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Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications
It is commonly known that alcoholism and alcohol intoxications are connected with severe violent crimes such as homicides. For instance, in Finland even 80 per cent of these crimes happen in alcohol intoxications. It has ...
Medicine & Health / Psychology & Psychiatry
Jun 01, 2009 |
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UF makes gene therapy advance in severe genetic disorder
A dog born with a deadly disease that prevents the body from using stored sugar has survived 20 months and is still healthy after receiving gene therapy at the University of Florida — putting scientists a step closer to finding ...
May 28, 2009 |
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