News tagged with growth factor
Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
Nov 02, 2009 |
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Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, ...
Study finds lack of VEGF can cause defects similar to dry macular degeneration
Nov 02, 2009 |
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Scientists at Schepens Eye Research Institute have found that when the eye is missing a diffusible form of vascular endothelial growth factor (VEGF), i.e. one that when secreted can reach other cells at a distance, the retina ...
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
Oct 16, 2009 |
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A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced ...
Scientists Discover A New Protein Partnership That Leads To Pediatric Tumor Regression
Medicine & Health / Neuroscience
Sep 10, 2009 |
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(PhysOrg.com) -- Why are some pediatric cancers able to spontaneously regress? Prof. Michael Fainzilber and his team of the Weizmann Institute's Biological Chemistry Department seem to have unexpectedly found part of the ...
Spare gene is fodder for fishes' evolution
Sep 03, 2009 |
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Scientists have suspected that spare parts in the genome—extra copies of functional genes that arise when genes or whole genomes get duplicated -- might sometimes provide the raw materials for the evolution ...
Prodrug could help curb skin toxicity related to EGFR-inhibiting cancer drugs
Sep 01, 2009 |
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There may be a way around the harsh skin toxicity associated with a widely used cancer drug, according to a study published online this week in Cancer Biology and Therapy by researchers from City of Hope and the Kimmel Cancer ...
Improvement of liver stem cell engraftment by protein delivery
Aug 24, 2009 |
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Researchers at INSERM (France) have engineered a chimeric protein that increases cell survival, migration and proliferation to improve stem cell engraftment. The results, which appear in the September 2009 issue of Experimental Bi ...
New treatments offer better survival and fresh challenges in colorectal cancer
Aug 21, 2009 |
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Colorectal cancer (CRC) is the second leading cause of cancer-related death in the Western world. Fortunately physicians today have an abundance of drug therapies available to improve survival length for more advanced cancer ...
Research points to new target for stopping colon cancer
Aug 17, 2009 |
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New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a ...
Study finds that lung cancer patients respond to erlotinib following cetuximab therapy
Aug 02, 2009 |
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Non-small cell lung cancer patients who have progressed on a cetuximab-containing regimen may respond to erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association ...
Iron-binding drug could help diabetics heal stubborn wounds
Jul 27, 2009 |
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A drug used to remove iron from the body could help doctors fight one of diabetes' cruelest complications: poor wound healing, which can lead to amputation of patients' toes, feet and even legs.
Drugs may prevent epilepsy, seizures after brain injury
Medicine & Health / Neuroscience
Jul 15, 2009 |
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(PhysOrg.com) -- Drugs that block a growth factor receptor on brain cells may prevent epilepsy after brain damage, according to a new study appearing in the July 15 issue of The Journal of Neuroscience.
A new take on growth factor signaling in tamoxifen resistance
Jun 24, 2009 |
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Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...
Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
Jun 01, 2009 |
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When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according ...
New treatment combination proves safe for head and neck cancer patients
May 31, 2009 |
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Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan ...
