News tagged with hdac inhibitors
Drug may slow spread of deadly eye cancer
A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers at Washington University School of Medicine in St. ...
Nov 28, 2011 |
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Tamoxifen resistance -- and how to defeat it
In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...
Nov 13, 2011 |
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'Shock and kill' research gives new hope for HIV-1 eradication
Latent HIV genes can be 'smoked out' of human cells. The so-called 'shock and kill' technique, described in a preclinical study in BioMed Central's open access journal Retrovirology, might represent a new milestone along ...
Medicine & Health / HIV & AIDS
Jun 04, 2009 |
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Search results for hdac inhibitors
Substance in cancer medicine could prevent heart attacks
A substance in medicines for cancer and epilepsy could also prevent heart attacks, according to researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, who have been using it to stimulate ...
Nov 23, 2011 |
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Benefit of novel drug in breast cancer seen in blood within weeks
Clinical benefit from use of a novel histone deacetylase inhibitor drug may be determined by examining blood cells days after a patient receives treatment. The drug, entinostat, is the first histone deacetylase inhibitor ...
Nov 13, 2011 |
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Connecting neurons to fix the brain
Each of the brain's 100 billion neurons forms thousands of connections with other neurons. These connections, known as synapses, allow cells to rapidly share information, coordinate their activities, and achieve ...
Medicine & Health / Neuroscience
Oct 26, 2011 |
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Study confirms safety, cancer-targeting ability of nutrient in broccoli, other vegetables
Sulforaphane, one of the primary phytochemicals in broccoli and other cruciferous vegetables that helps them prevent cancer, has been shown for the first time to selectively target and kill cancer cells while leaving normal ...
Jun 09, 2011 |
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New clinical trial to test novel approach to treat triple-negative breast cancer
A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive ...
Jun 02, 2011 |
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Drug can reverse overgrown hearts to help prevent heart failure
A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.
May 31, 2011 |
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'Fasting pathway' points the way to new class of diabetes drugs
A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards ...
May 12, 2011 |
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Innovative screening method identifies possible new treatment for fatal childhood disease
Many genes that cause human diseases have parallel genes in other organisms, including yeast. Now Columbia University researchers have used an innovative yeast-based screening method to identify a possible treatment for the ...
Apr 18, 2011 |
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Scientists devise targeted therapy strategy for rare form of childhood cancer
BOSTON--By "distracting" cancer proteins from their usual activity, scientists at Dana-Farber Cancer Institute and Brigham and Women's Hospital have caused cells in a rare, lethal form of cancer to begin behaving like normal ...
Mar 29, 2011 |
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Survival over single-line treatment improved with use of combo drug cancer therapy
A combination therapy for treating cancer discovered at the University of Colorado Cancer Center showed improved survival rates in patients with advanced non-small cell lung cancer (NSCLC), according to results from a double-blind, ...
Dec 14, 2010 |
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List of search results for hdac inhibitors