The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...
Biotechnology
Jun 23, 2022
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37
Throughout one's life, the blood is constantly being replenished from blood stem cells. However, these cells lose their functionality in old age. Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) ...
Cell & Microbiology
Jun 17, 2022
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31
The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
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136
In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them. Within the body, hematopoietic stem cells (HSCs) reside in their ...
Cell & Microbiology
Jun 9, 2022
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35
A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at ...
Cell & Microbiology
Jan 31, 2022
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103
Recently developed cell line is a potential source for generating endless amounts of red blood cells outside the body.
Cell & Microbiology
Dec 13, 2021
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62
Dormancy is a sleep-like state of cells that protects them from genetic damage and thus prolongs their survival. This state is reversible and characterized by low metabolic activity and division rate. Researchers from the ...
Biotechnology
Jun 23, 2021
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7
Hematopoietic stem/progenitor cells (HSPCs) include hematopoietic stem cells and several lineage-biased hematopoietic progenitor cells, which can provide all blood cell types in an adult organism. Among them, hematopoietic ...
Cell & Microbiology
Mar 26, 2021
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6
Researchers at Children's Hospital of Philadelphia (CHOP) have identified genes responsible for hematopoietic stem cell (HSC) regeneration via the assembly of the ribosome, the protein factories in cells that translate mRNA ...
Cell & Microbiology
Mar 11, 2021
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46
Researchers at the Center for Genomic Regulation (CRG) in Barcelona and Columbia University in New York City have identified a protein that is critical for the expansion of typically scarce, life-saving blood stem cells.
Cell & Microbiology
Dec 8, 2020
0
332
