News tagged with her2 receptor
Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer
May 28, 2009 |
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Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast ...
New radiation-free targeted therapy detects and eliminates breast cancer tumors in mice
Mar 30, 2009 |
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Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, ...
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Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
Oct 16, 2009 |
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A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced ...
Early stage, HER2-positive breast cancer patients at increased risk of recurrence
Dec 12, 2008 |
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Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, ...
Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
Nov 02, 2009 |
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Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, ...
Information about the use and accuracy of breast cancer tests is lacking, study finds
Sep 14, 2009 |
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A new study finds that there is little information available about the use of new testing technologies and targeted therapies in breast cancer, specifically the anti-cancer drug trastuzumab (Herceptin). Published in the November ...
Breast cancer etiology may vary by subtype
May 21, 2009 |
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Women's reproductive and lifestyle characteristics can be linked to different invasive breast cancer subtypes. Data on 2544 breast cancer cases, presented in the open access journal Breast Cancer Research, suggests that t ...
Risk of aggressive breast cancer subtype three times higher for black women
Mar 25, 2009 |
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Lifestyle, age and weight have all been considered as risk factors for breast cancer. Now a study published in the open access journal Breast Cancer Research has found that even taking these factors into consideration, black ...
Gene profiling predicts resistance to breast cancer drug Herceptin
Feb 20, 2007 |
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Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast ...
African-American women with advanced breast cancer often forego vital treatment
May 22, 2009 |
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A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies. Published in the July 1, 2009 issue of Cancer, a peer ...
Deactivating a cancer growth promoter
Sep 25, 2008 |
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Three enzymes called phosphatases that shut down a molecule called SRC-3 (steroid receptor coactivator 3) could provide a new pathway for fighting cancer, particularly tumors of the breast and prostate, said researchers at ...
Study shows use of Herceptin in treatment of stomach cancer prolongs life
Sep 25, 2009 |
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(PhysOrg.com) -- A study involving a University of Glasgow cancer specialist has found that using Herceptin increases survival rates among those with stomach cancer.
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