A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division.
Cell & Microbiology
Mar 7, 2024
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195
During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.
Molecular & Computational biology
Feb 26, 2024
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14
Chromatin is a unique DNA and protein complex that makes up the chromosomes. Specific proteins (histones) wind up the DNA like small cable drums to package the long DNA. A cable drum (consisting of four pairs of histones) ...
Plants & Animals
Feb 23, 2024
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58
Wheat, a globally important food crop, derives its yield from factors such as number of spikes per unit area, thousand-grain weight and grain yield per spike. Spike shape directly affects spikelet number, grain yield, and ...
Molecular & Computational biology
Feb 19, 2024
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83
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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2
DNA is the most important carrier of genetic information. Each cell contains approximately two meters of DNA. To ensure that all this genetic material fits into the small cell nucleus, it must be tightly packed. The DNA is, ...
Cell & Microbiology
Dec 4, 2023
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1
The "read–write" mechanism by which cells replicate and use chemical instructions for expressing genes has been uncovered by RIKEN researchers. The quality and quantity of gene expression correlates not only with instructions ...
Cell & Microbiology
Nov 7, 2023
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69
In eukaryotes, genomic DNA, which is a very long double helix containing all the genetic information, wraps around a globular protein called a histone and folds it many times before being contained within the nucleus.
Molecular & Computational biology
Sep 22, 2023
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1
Researchers led by Prof. Gan Haiyun from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) have documented the parental histones inheritance safeguard mechanism, in which parental ...
Cell & Microbiology
Sep 8, 2023
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36
When organisms pass their genes on to future generations, they include more than the code spelled out in DNA. Some also pass along chemical markers that instruct cells how to use that code. The passage of these markers to ...
Plants & Animals
Aug 28, 2023
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13
