News tagged with hiv antibodies

Two new antibodies found to cripple HIV: Potential key to AIDS vaccine

Medicine & Health / HIV & AIDS

Sep 03, 2009 | 5 / 5 (3) | 0

Researchers at and associated with the International AIDS Vaccine Initiative (IAVI), at The Scripps Research Institute, and at the biotechnology companies Theraclone Sciences and Monogram Biosciences have discovered two powerful ...

Scientists show why anti-HIV antibodies are ineffective at blocking infection

Medicine & Health / HIV & AIDS

Apr 22, 2009 | 5 / 5 (8) | 2

Some 25 years after the AIDS epidemic spawned a worldwide search for an effective vaccine against the human immunodeficiency virus (HIV), progress in the field seems to have effectively become stalled. The ...

Exhausted B cells fail to fight HIV

Medicine & Health / HIV & AIDS

Jul 14, 2008 | 4 / 5 (2) | 0

HIV tires out the cells that produce virus-fighting proteins known as antibodies, according to a human study that will be published online July 14 in the Journal of Experimental Medicine.

Researchers induce HIV-neutralizing antibodies that recognize HIV-1 envelope protein, lipids

Medicine & Health / HIV & AIDS

Sep 01, 2009 | not rated yet | 0

For the first time, researchers have experimentally induced antibodies that neutralize HIV-1 and simultaneously recognize both HIV-1 envelope protein and lipids. The results were reported by U.S. Military HIV Research Program ...

New strategy proposed for designing antibody-based HIV vaccine

Medicine & Health / HIV & AIDS

Jun 14, 2009 | not rated yet | 0

WHAT: Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. Attempts to create a vaccine that ...

New technology opens gateway to studying HIV-specific neutralizing antibodies

Medicine & Health / HIV & AIDS

Mar 16, 2009 | not rated yet | 0

Many scientists believe a vaccine that prevents HIV infection will need to stimulate the body to make neutralizing antibodies, infection-fighting proteins that prevent HIV from entering immune cells. Previous research has ...

HIV isolate from Kenya provides clues for vaccine design

Medicine & Health / HIV & AIDS

Jan 02, 2008 | 4 / 5 (3) | 0

Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine.

Scientists Find Rare, Potent Antibody to HIV-1

Medicine & Health / HIV & AIDS

Feb 23, 2009 | 5 / 5 (4) | 0

(PhysOrg.com) -- Scientists at Duke University Medical Center have for the first time isolated an important antibody in human serum that could potentially play a key role in the design of an AIDS vaccine. The research appears ...

New findings suggest strategy to help generate HIV-neutralizing antibodies

Medicine & Health / HIV & AIDS

Nov 19, 2009 | not rated yet | 0

New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute ...

How HIV vaccine might have increased odds of infection

Medicine & Health / HIV & AIDS

Nov 03, 2008 | not rated yet | 0

In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection. A new study by a team of researchers at the Montpellier ...

Study offers insights into failed HIV-1 vaccine trial

Medicine & Health / HIV & AIDS

Jul 20, 2009 | 5 / 5 (1) | 1

Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring ...

Exhausted B cells hamper immune response to HIV

Medicine & Health / HIV & AIDS

Jul 14, 2008 | not rated yet | 0

Recent studies have shown that HIV causes a vigorous and prolonged immune response that eventually leads to the exhaustion of key immune system cells--CD4+ and CD8+ T-cells--that target HIV. These tired cells become less ...

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