Human genome
hideThe human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs, while the remaining pair is sex-determining. The haploid human genome occupies a total of just over 3 billion DNA base pairs. The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences.
The haploid human genome contains an estimated 20,000–25,000 protein-coding genes, far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins, while the rest consists of RNA genes, regulatory sequences, introns and (controversially) "junk" DNA.
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News tagged with human genome
Genome advances promise personalized medical treatment
Nov 18, 2009 |
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A whirlwind of activity is under way to apply the findings of the $3 billion Human Genome Project to improve health care in the United States and around the world.
Singapore scientists describe novel method for 3-D whole genome mapping research
Nov 04, 2009 |
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In this week's Nature, Genome Institute of Singapore (GIS) scientists report a technological advance in the study of gene expression and regulation in the genome's three-dimensional folding and looping state through the de ...
Study sheds light on evolution of human complexity
Nov 03, 2009 |
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(PhysOrg.com) -- A painstaking analysis of thousands of genes and the proteins they encode shows that human beings are biologically complex, at least in part, because of the way humans evolved to cope with redundancies arising ...
Study conclusively ties rare disease gene to Parkinson's
Oct 21, 2009 |
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An international team led by a National Institutes of Health researcher has found that carriers of a rare, genetic condition called Gaucher disease face a risk of developing Parkinson's disease more than five times greater ...
What drives our genes? Researchers map the first complete human epigenome
Oct 14, 2009 |
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Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated. Now, researchers ...
Scientists use math modeling to predict unknown biological mechanism of regulation
Oct 14, 2009 |
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A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated - for the first time - that mathematical models created from data obtained by DNA microarrays, can ...
Gene data tool advances prospects for personalized medicine
Oct 09, 2009 |
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A sophisticated computational algorithm, applied to a large set of gene markers, has achieved greater accuracy than conventional methods in assessing individual risk for type 1 diabetes.
Establishing standard definitions for genome sequences
Oct 08, 2009 |
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In 1996, researchers from major genome sequencing centers around the world convened on the island of Bermuda and defined a finished genome as a gapless sequence with a nucleotide error rate of one or less ...
Scientists decipher the 3-D structure of the human genome
Oct 08, 2009 |
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(PhysOrg.com) -- Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds ...
Jumping genes, gene loss and genome dark matter
Oct 07, 2009 |
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In research published today by Nature, an international team describes the finest map of changes to the structure of human genomes and a resource they have developed for researchers worldwide to look at the ...
IBM Research Aims to Build Nanoscale DNA Sequencer (w/ Video)
Nanotechnology / Bio & Medicine
Oct 06, 2009 |
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(PhysOrg.com) -- In an effort to build a nanoscale DNA sequencer, IBM scientists are drilling nano-sized holes in computer-like chips and passing DNA strands through them in order to read the information contained ...
Complete Genomics deciphers 14 human genomes
Sep 09, 2009 |
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Complete Genomics, a Mountain View, Calif., startup, has announced that it had deciphered 14 full human genomes for customers that include pharmaceutical giant Pfizer and leading medical research institutes, a significant ...
Sharing the results of research critical to advancement of biological sciences
Sep 09, 2009 |
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Sharing the fruits of research in the biomedical sciences is critical for the advance of knowledge, yet with the advent of large-scale data gathering following the completion of the genome projects this is becoming harder ...
Scientists begin census of microbes: the trillions that live in or on us
Sep 02, 2009 |
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Scientists are beginning a large-scale effort to identify and analyze the vast majority of cells in or on your body that aren't of human origin.
Rutgers-Camden developing enzyme function database
Aug 26, 2009 |
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Since the advent of the Human Genome Project an explosion of data has sent the science world scrambling. There is a growing demand to fine-tune genomic codes, which list the "ingredients for life," but do not adequately explain ...
