News tagged with huntingtin gene

New drugs target delay of Huntington's symptoms

(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...

Chemistry / Biochemistry

created May 31, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Novel mouse model provides insight into rare neurodegenerative disease

New research sheds light on common pathogenic mechanisms shared by Huntington's disease (HD) and HD-like disorders. The study, published by Cell Press in the May 12, 2011, issue of the journal Neuron, uses a new transgenic mouse ...

Medicine & Health / Neuroscience

created May 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

Faulty clean-up process may be key event in Huntington's disease (w/ Video)

In a step towards a possible treatment for Huntington's disease, scientists at Albert Einstein College of Medicine of Yeshiva University have shown for the first time that the accumulation of a mutated protein may explain ...

Medicine & Health / Neuroscience

created Apr 11, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Researchers show efficacy of gene therapy in mouse models of Huntington's disease

Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's ...

Medicine & Health / Neuroscience

created Oct 30, 2009 | popularity 5 / 5 (2) | comments 0

Huntington's disease deciphered

Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings ...

Medicine & Health / Neuroscience

created Jun 14, 2009 | popularity 5 / 5 (6) | comments 0

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality ...

Medicine & Health / Genetics

created Apr 09, 2009 | popularity not rated yet | comments 0

Modification of mutant huntingtin protein increases its clearance from brain cells

A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...

Medicine & Health / Research

created Apr 02, 2009 | popularity 5 / 5 (3) | comments 0