News tagged with huntingtin gene
Researchers show efficacy of gene therapy in mouse models of Huntington's disease
Medicine & Health / Neuroscience
Oct 30, 2009 |
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Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's ...
Huntington's disease deciphered
Medicine & Health / Neuroscience
Jun 14, 2009 |
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Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings ...
New therapeutic strategy could target toxic protein in most patients with Huntington's disease
Apr 09, 2009 |
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Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality ...
Search results for huntingtin gene
Modification of mutant huntingtin protein increases its clearance from brain cells
Apr 02, 2009 |
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A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...
Mystery solved: Tiny protein-activator responsible for brain cell damage in Huntington disease
Jun 04, 2009 |
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Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington's disease (HD), but only kills cells in the part of the brain that controls movement, ...
'Intrabody' can mop up mutant protein in Huntington's disease model
May 26, 2008 |
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Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" ...
Huntington's disease study shows animal models on target
Jul 31, 2007 |
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An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington’s Disease (HD) closely resembles that of human HD patients.
A new molecular zip code, and a new drug target for Huntington's disease
Aug 20, 2007 |
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McMaster University researchers have first insight into how Huntington's disease (HD) is triggered. The research will be published online in the British Journal, Human Molecular Genetics, on Monday, August 20.
Study links faulty DNA repair to Huntington's disease onset
Apr 23, 2007 |
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Huntington’s disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. But a new discovery about how cells repair their DNA points to a possible way to ...
Scientists encourage cells to make a meal of Huntington's disease
May 07, 2007 |
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Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.
Small molecules might block mutant protein production in Huntington's disease
May 03, 2009 |
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Molecules that selectively interfere with protein production can stop human cells from making the abnormal molecules that cause Huntington's disease, researchers at UT Southwestern Medical Center have found.
Huntington disease begins to take hold early on
Apr 16, 2009 |
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A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder. For example, profound changes (comparable to those ...
Study suggests new treatments for Huntington's disease
Jan 09, 2008 |
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Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington’s disease causes neurodegeneration. They have also manipulated the flies to successfully suppress that neurodegeneration, ...
List of search results for huntingtin gene
