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Hyaluronan

Hyaluronan (also called hyaluronic acid or hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions. One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.

The average 70 kg (154 lbs) person has roughly 15 grams of hyaluronan in the body, one-third of which is turned over (degraded and synthesized) every day. Hyaluronic acid is also a component of the group A streptococcal extracellular capsule, and is believed to play a role in virulence.

For more information about Hyaluronan, read the full article at Wikipedia.
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Researchers learn how lung fibrosis begins and could be treated

An invasive cell that leads to fibrosis of the lungs may be stopped by cutting off its supply of sugar, according to researchers at Duke University Medical Center.

Medicine & Health / Research

created Jun 27, 2011 | popularity not rated yet | comments 0 | with audio podcast

Ubiquitous sugar molecule could be key to repairing deep wound without scarring

Blocking fragments of the sugar molecule hyaluronan that triggers inflammation could be the key to robust healing and less scarring in deep wounds, Canadian researchers reported at the American Society for Cell Biology's ...

Medicine & Health / Research

created Dec 12, 2010 | popularity 5 / 5 (2) | comments 0

Research Finds New Cause of Ozone Wheezing and Potential Treatments

(PhysOrg.com) -- Researchers at the Duke University Medical Center and the National Institute of Environmental Health Sciences (NIEHS) discovered a cause of airway irritation and wheezing after exposure to ozone, a common ...

Chemistry /

created Feb 03, 2009 | popularity not rated yet | comments 0




Search results for hyaluronan


Scientists: Lions and tigers roar a bit like babies cry

When lions and tigers roar loudly and deeply – terrifying every creature within earshot – they are somewhat like human babies crying for attention, although their voices are much deeper.

Biology / Plants & Animals

created Nov 02, 2011 | popularity not rated yet | comments 2 | with audio podcast

Simpler, less-expensive detection kit for osteoarthritis, liver disease, and cancer developed

A research team from Chiang Mai University (CMU) have developed a simpler, less-expensive Detection Kit for monitoring Hyaluronan using purified protein from the waste cartilage of a variety of species from the meat processing ...

Medicine & Health / Research

created Apr 21, 2011 | popularity 4 / 5 (1) | comments 0

A mutation causing wrinkled skin of Shar-Pei dogs is linked to periodic fever disorder

An international investigation has uncovered the genetics of the Shar-Pei dog's characteristic wrinkled skin. The researchers, led by scientists at Uppsala University and the Broad Institute, have connected this mutation ...

Biology / Biotechnology

created Mar 17, 2011 | popularity not rated yet | comments 1 | with audio podcast

Monitoring wear in helicopters -- and hips, knees and ankles, too

Ferrography, a practice used by the American and Israeli air forces to monitor the condition of machinery, extracts tiny iron particles from lubricants such as oil and grease to analyze wear in machines. Determining whether ...

Medicine & Health / Research

created Nov 23, 2010 | popularity not rated yet | comments 0

Nano-Vehicle acts as cluster bomb for tumors

Chemotherapy, while an effective cancer treatment, also brings debilitating side effects such as nausea, liver toxicity, and a battered immune system. Now, a new way to deliver this life-saving therapy to cancer patients ...

Nanotechnology / Bio & Medicine

created Sep 18, 2010 | popularity 4.5 / 5 (22) | comments 4 | with audio podcast

Removing wrinkles with RHAMM

Hollywood stars of a certain age take note: Research at Berkeley Lab suggests that a protein linked to the spread of several major human cancers may also hold great potential for the elimination of wrinkles ...

Medicine & Health / Other

created Feb 11, 2009 | popularity 5 / 5 (1) | comments 0

Healing process found to backfire in lung patients

A mechanism in the body which typically helps a person heal from an injury, may actually be causing patients with idiopathic pulmonary fibrosis (IPF) to get worse, researchers at the National Institute of Environmental Health ...

Medicine & Health / Other

created Oct 27, 2008 | popularity 4 / 5 (1) | comments 0

Printers to produce life-saving organs

A team of American scientists is studying the potential of printers being developed to produce life-saving organs, reports Wired.com. They believe that any organ, a skin graft, a new trachea or a heart patch ...

Other Sciences /

created Dec 12, 2005 | popularity 4.9 / 5 (16) | comments 0


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