Immunosuppressive drug
hideImmunosuppressive drugs or immunosuppressive agents are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:
These drugs are not without side-effects and risks. Because the majority of them act non-selectively, the immune system is less able to resist infections and the spread of malignant cells. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, liver, and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.
Immunosuppressive drugs can be classified into five groups:
For more information about Immunosuppressive drug, read the full article at
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News tagged with immunosuppressive drugs
Childhood kidney disorder has lasting effects
Sep 24, 2009 |
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A kidney condition that can arise in children and was until recently believed to disappear after puberty may persist into adulthood and cause significant long-term complications, according to a study appearing in an upcoming ...
Post-transplant combo can replace toxic immune-suppressing drugs in monkeys
Jul 08, 2009 |
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Transplant patients rely on drugs to prevent graft rejection, but at the cost of serious side effects. The class of immunosuppressive drugs known as calcineurin inhibitors (examples are cyclosporine and tacrolimus) can damage ...
'Nature vs. nurture' study of deceased donor pairs in kidney transplantation
Apr 22, 2009 |
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The implications of a new study could improve the outcomes, and potentially survival rates, for some of the thousands of individuals who undergo kidney transplants each year. The study concluded that donor-related risk factors, ...
Major breakthrough in transplantation immunity
Apr 07, 2009 |
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Australian scientists have made a discovery that may one day remove the need for a lifetime of toxic immunosuppressive drugs after organ transplants.
New urine test detects common cause of kidney transplant failure
Jan 21, 2009 |
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A new and simple urine test can detect polyomavirus nephropathy, a relatively new and serious complication that affects up to 9% of kidney transplant recipients, according to a study appearing in the February 2009 issue of ...
