Inflammation
hideInflammation (Latin, inflamatio, to set on fire) is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. Inflammation is not a synonym for infection. Even in cases where inflammation is caused by infection, the two are not synonymous: infection is caused by an exogenous pathogen, while inflammation is the response of the organism to the pathogen.
In the absence of inflammation, wounds and infections would never heal and progressive destruction of the tissue would compromise the survival of the organism. However, an inflammation that runs unchecked can also lead to a host of diseases, such as hay fever, atherosclerosis, and rheumatoid arthritis. It is for that reason that inflammation is normally closely regulated by the body.
Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process.
For more information about Inflammation, read the full article at
Wikipedia.
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News tagged with inflammatory diseases
Scientists discover cells that control inflammation in chronic disease
Nov 17, 2009 |
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(PhysOrg.com) -- A new type of immune cell that can be out of control in certain chronic inflammatory diseases, worsening the symptoms of conditions like psoriasis and asthma, is described for the first time ...
Genome sequence for the domestic horse unveiled
Nov 05, 2009 |
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The whole genome sequence of the domestic horse has been completed by the genome-sequencing center of The Broad Institute of MIT and Harvard, in collaboration with an international team of researchers that ...
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Study describes new tool in the fight against autoimmune diseases, blood cancers
13 hours ago |
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A study led by a Scripps Research Institute scientist describes a new, highly pragmatic approach to the identification of molecules that prevent a specific type of immune cells from attacking their host. The findings add ...
Tobacco smoke exposure before heart transplantation may increase the risk of transplant failure
Nov 24, 2009 |
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A study conducted at the University of Maryland School of Medicine in Baltimore provides the first direct evidence that cigarette smoke exposure prior to a heart transplant in either the donor, recipient, or both, accelerates ...
Polyphenols and polyunsaturated fatty acids boost the birth of new neurons
Nov 24, 2009 |
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Universitat Autňnoma de Barcelona (UAB, Spain) researchers have confirmed that a diet rich in polyphenols and polyunsaturated fatty acids, patented as an LMN diet, helps boost the production of the brain's stem cells ...
Factors from common human bacteria may trigger multiple sclerosis
Nov 24, 2009 |
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Current research suggests that a common oral bacterium may exacerbate autoimmune disease. The related report by Nichols et al, "Unique Lipids from a Common Human Bacterium Represent a New Class of TLR2 Ligands Capable of ...
Surface bacteria maintain skin's healthy balance
Nov 22, 2009 |
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On the skin's surface, bacteria are abundant, diverse and constant, but inflammation is undesirable. Research at the University of California, San Diego School of Medicine now shows that the normal bacteria living on the ...
Can EP4 agonist alleviate gastric lesions?
Nov 18, 2009 |
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Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. To mitigate NSAIDs' ...
Researchers find inflammation critical in aortic dissection
Nov 16, 2009 |
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The aorta, the body's largest artery, stretches from the chest to below the kidneys, expanding and contracting with the pressure of blood driven directly into it by the heart. Although its walls are extraordinarily strong, ...
Antioxidant found in vegetables has implications for treating cystic fibrosis
Nov 16, 2009 |
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Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the ...
Study shows link between influenza virus and fever
Nov 16, 2009 |
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One feature of the "new influenza" is a sudden rise in temperature. Up to now it was not exactly understood how this reaction occurs. Scientists at the University of Bonn and the Technical University of Munich, Germany, have ...
How cells tolerate DNA damage -- start signal for cell survival program identified
Nov 16, 2009 |
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Cancer researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained new insights into how cells react to DNA damage. Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit ...
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