How promiscuous protein droplets regulate immune genes

Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its orientation and local environment. New research demonstrates that the glucocorticoid receptor ...

New mechanism for anti-infection effects of dietary fiber

New research in mice has uncovered a previously unknown interaction between molecules derived from dietary fiber and an immune cell protein, which triggers protection against infection with Salmonella bacteria. Hitoshi Tsugawa ...

Influenza virus-induced oxidized DNA activates inflammasomes

Both influenza virus M2, a proton-selective ion channel essential for efficient viral replication, and PB1-F2 protein, which localizes to the mitochondria and attenuates host antiviral immunity, are involved in the inflammatory ...

Re-trafficking proteins to fight Salmonella infections

When humans get infected by pathogenic bacteria, the body's immune system tries to eliminate the intruders. One way of doing this is by launching an inflammatory response—a cascade of events that includes the expression ...

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