Cancer cells are more dependent on a cellular garbage disposal unit—the proteasome—than healthy cells, and cancer therapies take advantage of this dependency. Scientists at EMBL and MPI determined the proteasome's 3D ...
Biochemistry
Aug 4, 2016
0
872
Scientists have made a major breakthrough in the global search for a new drug to beat the malaria parasite's growing resistance to first-defence treatments.
Biochemistry
Feb 10, 2016
0
34
Doping in the horseracing industry has spurred regulations banning performance-enhancing drugs, as well as calls for an anti-doping agency in the U.S. But as in human sports, testing for certain kinds of prohibited substances ...
Analytical Chemistry
Jan 13, 2016
0
9
Protease inhibitors are a class of antiviral drugs that are commonly used to treat HIV, the virus that causes AIDS. Scientists at the University of Nebraska Medical Center designed a new delivery system for these drugs that, ...
Bio & Medicine
Oct 19, 2015
2
106
A group of researchers at the University of California, Berkeley have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs.
Cell & Microbiology
Nov 15, 2012
0
0
(Phys.org)—Research led by the University of Bath has identified two possible new routes for developing novel drugs for high blood pressure and heart disease.
Biochemistry
Oct 10, 2012
0
0
Fish exhibit abnormal behavior and lower levels of anxiety when exposed to Selective Serotonin Reuptake Inhibitors (SSRI), which are common drugs used to treat depression, among other disorders. The study, by Baylor University ...
Ecology
Mar 6, 2012
2
0
(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...
Biotechnology
Feb 20, 2012
0
0
Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...
Biochemistry
Feb 16, 2012
0
0
Four new anti-cancer drug leads have been identified in a research paper published online this week in Bioorganic and Medicinal Chemistry.
Biochemistry
Nov 28, 2011
1
0
