News tagged with inhibitors
Commentary warns of unexpected consequences of proton pump inhibitor use in reflux disease
Nov 03, 2009 |
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Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these ...
Link Between Antidepressants and Birth Defect
Sep 29, 2009 |
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(PhysOrg.com) -- Researchers in Denmark have studied almost half a million Danish children and found a slightly higher rate of septal heart abnormalities in babies whose mothers took an SSRI antidepressant ...
New studies point to strategies for reducing painful breast cancer drug side effects
Sep 28, 2009 |
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Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines. ...
Switching early breast cancer patients to exemestane improves long-term survival
Sep 21, 2009 |
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New research has found that switching post-menopausal women with early breast cancer to the drug exemestane (Aromasin) after two or three years of tamoxifen rather than keeping them on tamoxifen for five years improves the ...
Lipid involved with gene regulation uncovered
Sep 08, 2009 |
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(PhysOrg.com) -- Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that ...
Researchers restore missing protein in rare genetic brain disorder
Sep 06, 2009 |
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UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, ...
Mutation in renin gene linked to inherited kidney disease
Aug 18, 2009 |
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A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study by researchers at Wake Forest University School of Medicine, Charles University in Prague and colleagues.
Some blood pressure drugs may help protect against dementia, study shows
Medicine & Health / Medications
Jul 23, 2009 |
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A particular class of medication used to treat high blood pressure could protect older adults against memory decline and other impairments in cognitive function, according to a newly published study from Wake Forest University ...
Acid-reducing medicines may lead to dependency
Jul 01, 2009 |
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Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals, according to a new study in Gastroenterology, th ...
New piece found in colorectal cancer puzzle
Jun 25, 2009 |
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Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the ...
'Shock and kill' research gives new hope for HIV-1 eradication
Medicine & Health / HIV & AIDS
Jun 04, 2009 |
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Latent HIV genes can be 'smoked out' of human cells. The so-called 'shock and kill' technique, described in a preclinical study in BioMed Central's open access journal Retrovirology, might represent a new milestone along ...
Antidepressant does not stop repetitive behaviors in autistic children
Medicine & Health / Psychology & Psychiatry
Jun 01, 2009 |
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The antidepressant citalopram does not appear to reduce the occurrence of repetitive behaviors in children and teens with autism spectrum disorders, according to a report in the June issue of Archives of General Psychiatry.
New mouse model of depression/anxiety enhances understanding of antidepressant drugs
Medicine & Health / Neuroscience
May 27, 2009 |
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A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety. ...
Determining success or failure in cholesterol-controlling drugs
May 15, 2009 |
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Researchers at the University of California, San Diego have discovered that a complex network of interactions between drugs and the proteins with which they bind can explain adverse drug effects. Their findings suggest that ...
Study shows benefits of anti-clotting medications reduced by common heartburn drugs
Medicine & Health / Medications
May 06, 2009 |
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The anti-clotting action of the medication clopidogrel (Plavix) can be compromised by common drugs for the treatment of heartburn and ulcers resulting in a roughly 50% increase in the combined risk of hospitalization for ...
