News tagged with inhibitors
A new mouse could help understand how some lung cancer cells evade drug treatment
Dec 09, 2009 |
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Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor ...
Second-line CML drugs evoke faster response than front-line therapy
Dec 07, 2009 |
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Two medications approved as treatment for drug-resistant chronic myeloid leukemia continue to provide patients with quicker, better responses as a first treatment than the existing front-line drug, researchers at The University ...
Drug shows promise for T315I-mutated chronic myeloid leukemia
Dec 07, 2009 |
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Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. ...
Researchers identify new mechanism of blocking HIV-1 from entering cells
Medicine & Health / HIV & AIDS
Nov 30, 2009 |
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Publishing in PLoS Pathogens, researchers at from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.
Serotonin Made in Breast Cancer Cells, Researchers Show
Nov 24, 2009 |
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(PhysOrg.com) -- Researchers at the University of Cincinnati have documented that the brain hormone serotonin is made in human breast cancer cells and functions abnormally, contributing to malignant growth.
Commentary warns of unexpected consequences of proton pump inhibitor use in reflux disease
Nov 03, 2009 |
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Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these ...
Link Between Antidepressants and Birth Defect
Sep 29, 2009 |
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(PhysOrg.com) -- Researchers in Denmark have studied almost half a million Danish children and found a slightly higher rate of septal heart abnormalities in babies whose mothers took an SSRI antidepressant ...
New studies point to strategies for reducing painful breast cancer drug side effects
Sep 28, 2009 |
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Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines. ...
Switching early breast cancer patients to exemestane improves long-term survival
Sep 21, 2009 |
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New research has found that switching post-menopausal women with early breast cancer to the drug exemestane (Aromasin) after two or three years of tamoxifen rather than keeping them on tamoxifen for five years improves the ...
Lipid involved with gene regulation uncovered
Sep 08, 2009 |
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(PhysOrg.com) -- Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that ...
Researchers restore missing protein in rare genetic brain disorder
Sep 06, 2009 |
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UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, ...
Mutation in renin gene linked to inherited kidney disease
Aug 18, 2009 |
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A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study by researchers at Wake Forest University School of Medicine, Charles University in Prague and colleagues.
Some blood pressure drugs may help protect against dementia, study shows
Medicine & Health / Medications
Jul 23, 2009 |
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A particular class of medication used to treat high blood pressure could protect older adults against memory decline and other impairments in cognitive function, according to a newly published study from Wake Forest University ...
Acid-reducing medicines may lead to dependency
Jul 01, 2009 |
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Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals, according to a new study in Gastroenterology, th ...
New piece found in colorectal cancer puzzle
Jun 25, 2009 |
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Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the ...
