News tagged with inhibitors
A new mouse could help understand how some lung cancer cells evade drug treatment
Dec 09, 2009 |
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Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor ...
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Validity of cost-effectiveness models based on randomized clinical trials
Dec 08, 2009 |
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Cost-effectiveness studies are widely used to guide prescribing policy in many countries, as part of health technology assessment programmes. However, a new study published this week in PLoS Medicine by Tjeerd-Pieter van St ...
Clinical trial advances new approach to re-sensitizing breast cancer
Dec 13, 2009 |
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A new drug cocktail might be the right mix to fight breast cancer after it becomes resistant to standard therapy. Details of a new study supporting this approach suggest it's possible to re-sensitize tumors thus allowing ...
Small addition to cancer drug may make big difference
Dec 08, 2009 |
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University of Florida researchers have found a way to use just a fraction of the normal dosage of a highly toxic, debilitating chemotherapy drug to achieve even better results against colon cancer cells.
Dermatologic infections in cancer patients treated with EGFRI therapy
Dec 09, 2009 |
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Patients who experience dermatologic toxic effects from epidermal growth factor receptor inhibitors (EGFRIs) have a high prevalence of skin and nail infections, according to a new study published online December 9 in the ...
Low cholesterol transfer protein activity associated with heart disease risk
12 minutes ago |
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Although seen as a potential heart disease therapy, raising high-density lipoprotein (HDL) cholesterol levels by inhibiting activity of a transfer protein may not be effective, a new study suggests. Scientists at the Jean ...
Combination therapy with midostaurin improves survival of AML patients with FLT3 mutations, phase 1
Dec 08, 2009 |
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A targeted drug that is active against acute myeloid leukemia (AML) is particularly effective when teamed with chemotherapy in patients whose cancer cells harbor a key genetic mutation, researchers at Dana-Farber Cancer Institute ...
Most Oncologists Feel New Genetic Test for Tamoxifen Sensitivity Not Ready for the Clinic
Dec 11, 2009 |
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(PhysOrg.com) -- Despite commercial availability and direct to consumer marketing of a new genetic test designed to reveal a breast cancer patient’s sensitivity to tamoxifen, most physicians in the U.S. are not currently ...
ASGE issues guidelines on management of antithrombotic agents for endoscopic procedures
Dec 08, 2009 |
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According to a new guideline from the American Society for Gastrointestinal Endoscopy (ASGE) regarding the management of antithrombotic agents for endoscopy, aspirin and/or NSAIDs may be continued for all elective endoscopic ...
Coaxing injured nerve fibers to regenerate by disabling 'brakes' in the system
Medicine & Health / Neuroscience
Dec 09, 2009 |
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Brain and spinal-cord injuries typically leave people with permanent impairment because the injured nerve fibers (axons) cannot regrow. A study from Children's Hospital Boston, published in the December 10 ...
Most antidepressants miss key target of clinical depression
Medicine & Health / Psychology & Psychiatry
Dec 08, 2009 |
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A key brain protein called monoamine oxidase A (MAO-A) - is highly elevated during clinical depression yet is unaffected by treatment with commonly used antidepressants, according to an important study published today in ...
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