News tagged with inhibitors
Serotonin Made in Breast Cancer Cells, Researchers Show
Nov 24, 2009 |
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(PhysOrg.com) -- Researchers at the University of Cincinnati have documented that the brain hormone serotonin is made in human breast cancer cells and functions abnormally, contributing to malignant growth.
Drug shows promise for T315I-mutated chronic myeloid leukemia
Dec 07, 2009 |
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Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. ...
Some blood pressure drugs may help protect against dementia, study shows
Medicine & Health / Medications
Jul 23, 2009 |
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A particular class of medication used to treat high blood pressure could protect older adults against memory decline and other impairments in cognitive function, according to a newly published study from Wake Forest University ...
Scientists ID gene key to Alzheimer's-like reversal
May 06, 2009 |
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(PhysOrg.com) -- A team led by researchers at MIT's Picower Institute for Learning and Memory has now pinpointed the exact gene responsible for a 2007 breakthrough in which mice with symptoms of Alzheimer's disease regained ...
Researchers identify new mechanism of blocking HIV-1 from entering cells
Medicine & Health / HIV & AIDS
Nov 30, 2009 |
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Publishing in PLoS Pathogens, researchers at from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.
A new mouse could help understand how some lung cancer cells evade drug treatment
Dec 09, 2009 |
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Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor ...
Researchers restore missing protein in rare genetic brain disorder
Sep 06, 2009 |
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UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, ...
Second-line CML drugs evoke faster response than front-line therapy
Dec 07, 2009 |
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Two medications approved as treatment for drug-resistant chronic myeloid leukemia continue to provide patients with quicker, better responses as a first treatment than the existing front-line drug, researchers at The University ...
Link Between Antidepressants and Birth Defect
Sep 29, 2009 |
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(PhysOrg.com) -- Researchers in Denmark have studied almost half a million Danish children and found a slightly higher rate of septal heart abnormalities in babies whose mothers took an SSRI antidepressant ...
Licorice compound offers new cancer prevention strategy
Mar 23, 2009 |
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A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.
Passover's matzoh ball soup may be good for your health
Apr 02, 2009 |
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With the Jewish holiday of Passover beginning at sundown next Wednesday, April 8, a staple of the traditional dinner -- chicken soup with matzoh balls -- may take on medicinal importance based on findings ...
New view of HIV entry may lead to next generation of inhibitors
Medicine & Health / HIV & AIDS
Apr 30, 2009 |
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Scientists may need to rethink the design of drugs meant to block HIV from infecting human cells, according to a study that appears in the May 1st issue of the journal Cell, a Cell Press publication. That's because the ne ...
New mouse model of depression/anxiety enhances understanding of antidepressant drugs
Medicine & Health / Neuroscience
May 27, 2009 |
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A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety. ...
Inhibiting proteins may prevent cartilage breakdown in arthritis patients
Feb 18, 2009 |
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Current arthritis medications can ease the pain, but stopping the progression of the disease requires more aggressive treatments: use of very limited available drugs or surgical intervention. University of Missouri researchers ...
Lipid involved with gene regulation uncovered
Sep 08, 2009 |
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(PhysOrg.com) -- Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that ...
