News tagged with interleukin 1

Clinical trial demonstrates that rilonacept significantly reduces gout flares

A phase II clinical trial found that rilonacept, an inhibitor of the protein interleukin-1 (IL-1), significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy. Results of the trial—the ...

Medicine & Health / Diseases

created Jan 05, 2012 | popularity not rated yet | comments 0

New genetic links to MS also play roles in other autoimmune diseases

Results of the largest genomics study of multiple sclerosis patients ever undertaken have identified more than two dozen new genetic variants linked to disease risk, including some previously implicated in other autoimmune ...

Medicine & Health / Genetics

created Aug 10, 2011 | popularity 5 / 5 (2) | comments 0

Gene therapy reverses type 1 diabetes in mice

An experimental cure for Type 1 diabetes has a nearly 80 percent success rate in curing diabetic mice. The results, to be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston, offer possible hope of ...

Medicine & Health / Research

created Jun 06, 2011 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Protein levels could signal that a child will develop diabetes

Decreasing blood levels of a protein that helps control inflammation may be a red flag that could help children avoid type 1 diabetes, researchers say.

Medicine & Health / Research

created Apr 25, 2011 | popularity not rated yet | comments 1

Dual role for immune cells in the brain

We all have at one time or another experienced the typical signs of an infection: the fever, the listlessness, the lack of appetite. They are orchestrated by the brain in response to circulating cytokines, ...

Medicine & Health / Neuroscience

created Jan 13, 2010 | popularity 4.4 / 5 (5) | comments 0 | with audio podcast

Study shows link between influenza virus and fever

One feature of the "new influenza" is a sudden rise in temperature. Up to now it was not exactly understood how this reaction occurs. Scientists at the University of Bonn and the Technical University of Munich, Germany, have ...

Medicine & Health / Research

created Nov 16, 2009 | popularity 5 / 5 (1) | comments 0

Polymorphisms of the interleukin-1 gene complex may influence alcohol dependence

Cytokines are small proteins secreted by cells that serve as molecular messengers between cells. Pro-inflammatory cytokines - which function in the immune system - may be involved in alcohol dependence (AD). A study of ...

Medicine & Health / Research

created Sep 18, 2009 | popularity not rated yet | comments 0

Endothelin-1 inhibitors in chronic pancreatitis

Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates ...

Medicine & Health / Cancer

created Sep 17, 2009 | popularity not rated yet | comments 0

Study finds molecular link between insulin resistance and inflammation

An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh ...

Medicine & Health / Research

created Aug 26, 2009 | popularity 5 / 5 (1) | comments 0

Immune system researchers win $500K medical prize

(AP) -- The nation's richest prize in medicine and biomedical research was awarded Friday to three immune system researchers for work that led to new treatments for rheumatoid arthritis and diabetes.

Medicine & Health / Other

created Apr 24, 2009 | popularity 5 / 5 (1) | comments 0

Biomarkers detected for Chikungunya fever

Three specific biomarkers provide an accurate indication of the severity of Chikungunya fever (CHIKF), which is emerging as a threat in South-East Asia, the Pacific and Europe, according to research conducted in Singapore.

Biology / Cell & Microbiology

created Mar 04, 2009 | popularity not rated yet | comments 0

Study shows benefits of hormone found in fat tissue

It's called the obesity paradox. Although obese people are more apt to suffer from inflammatory diseases, such as diabetes, heart disease, and stroke, they are also more likely to survive a major attack caused by one of those ...

Medicine & Health / Research

created Feb 26, 2009 | popularity 5 / 5 (2) | comments 0