News tagged with interleukin
Drug halts organ damage in inflammatory genetic disorder
A new study shows that Kineret (anakinra), a medication approved for the treatment of rheumatoid arthritis, is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease ...
Medicine & Health / Medications
Feb 10, 2012 |
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The butterfly effect in nanotech medical diagnostics
Tiny metallic nanoparticles that shimmer in the light like the scales on a butterfly's wing are set to become the color-change components of a revolutionary new approach to point-of-care medical diagnostics, according to ...
Nanotechnology / Bio & Medicine
Feb 06, 2012 |
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Mutated Kras spins a molecular loop that launches pancreatic cancer
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms ...
Jan 26, 2012 |
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Inflammation may link obesity and adverse pregnancy outcomes
A number of different immunological mechanisms ensure the successful establishment and maintenance of pregnancy. Imbalance in these mechanisms is associated with adverse pregnancy outcomes. In a review published in Advances in ...
Jan 10, 2012 |
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Clinical trial demonstrates that rilonacept significantly reduces gout flares
A phase II clinical trial found that rilonacept, an inhibitor of the protein interleukin-1 (IL-1), significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy. Results of the trial—the ...
Jan 05, 2012 |
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New study shows how B cells may generate antibodies after vaccination
Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B ...
Dec 15, 2011 |
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Research describes advantages of new vaccine adjuvant
New research from the laboratory of Dr. Elizabeth Leadbetter at the Trudeau Institute may lead to a whole new class of vaccines. Dr. Leadbetter's lab has discovered new properties of a potential vaccine adjuvant that suggest ...
Dec 12, 2011 |
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New research shows how viruses use 'good' gut bacteria to bypass immune system
(PhysOrg.com) -- Two new studies demonstrate how viruses, such as the one responsible for polio, use good bacteria in the human (or mouse) gut to evade detection by the immune system.
Oct 14, 2011 |
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Study discovers new targets for treating inflammatory, autoimmune diseases
Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway ...
Oct 07, 2011 |
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Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients
Melanoma of the eye (ocular or uveal melanoma) frequently spreads to the liver and, once this has happened, there is no effective treatment and patients die within an average of two to four months. Only about one in ten patients ...
Sep 23, 2011 |
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New genetic links to MS also play roles in other autoimmune diseases
Results of the largest genomics study of multiple sclerosis patients ever undertaken have identified more than two dozen new genetic variants linked to disease risk, including some previously implicated in other autoimmune ...
Aug 10, 2011 |
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Obese dieters' brain chemistry works against their weight-loss efforts
If you've been trying to lose weight and suspect your body's working against you, you may be right, according to a University of Illinois study published in Obesity.
Jun 23, 2011 |
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Transcription factor regulates protein that dampens immune responses
Interleukin-10 (IL-10) is an anti-inflammatory cytokine protein that reduces immune responses and staves off autoimmune disease. Now, a research team led by Masato Kubo at the RIKEN Research Center for Allergy ...
Jun 17, 2011 |
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Researchers find potential new way to fight sepsis
By digging a little deeper, researchers may have found a potential target for reversing the deadly blood infection sepsis.
Jun 10, 2011 |
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Gene therapy reverses type 1 diabetes in mice
An experimental cure for Type 1 diabetes has a nearly 80 percent success rate in curing diabetic mice. The results, to be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston, offer possible hope of ...
Jun 06, 2011 |
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Interleukin
Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes), The term interleukine, (inter-) as a means of communication, (-leukin) deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes. The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells.
For more information about Interleukin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
