Because iPS cells can be made into just about any cell type in the body, they have great promise for cell therapies. One major problem, however, is that not all reprogramming cells successfully become iPS cells, resulting ...
Biotechnology
Jan 6, 2022
0
68
The original iPS cells were reprogrammed by transducing four genes: OCT3/4, SOX2, KLF4, and c-MYC. Later experiments would show that c-MYC can be replaced with MYCL. Both are MYC proteins and thus oncogenes, but animal experiments ...
Cell & Microbiology
Dec 21, 2021
0
8
Brain organoids are models of the brain made from growing stem cells like iPS cells into three-dimensional structures. They are used to study all sorts of brain-related phenomenon, including neural networks and disease development. ...
Cell & Microbiology
Oct 28, 2021
0
56
A new bioinformatics tool, MHcut, developed by researchers in Kyoto, Japan, and Montreal, Canada, reveals that a natural repair system for DNA damage, microhomology-mediated end joining, is probably far more common in humans ...
Biotechnology
Oct 28, 2019
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5
FUJIFILM Corporation has successfully developed intestinal epithelial cells derived from human iPS cells for optimal use in assessing drug absorption in joint research conducted with Nagoya City University (Graduate School ...
Cell & Microbiology
Sep 27, 2018
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4
Researchers at the School of Medicine have identified a new protein critical to the production of induced pluripotent stem cells, or iPS cells.
Cell & Microbiology
Jul 17, 2018
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280
Vincent Pasque from KU Leuven, Belgium, and Kathrin Plath from UCLA led an international study into how specialized cells are reprogrammed to induced pluripotent stem cells (iPS). The researchers discovered that female and ...
Cell & Microbiology
Apr 19, 2018
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146
Researchers led by Dr. Knut Woltjen report a new gene editing method that can modify a single DNA base in the human genome with absolute precision. The technique, which is described in Nature Communications, is unique in ...
Biotechnology
Mar 5, 2018
1
330
Researchers who work with stem cells have ambitious goals. Some want to cure cancer or treat heart disease. Others want to grow the tissues and organs that patients need for transplants. Some groups are even working to develop ...
Cell & Microbiology
Feb 14, 2018
0
70
In 2012, a Japanese research group discovered that human skin cells acquire pluripotency when introduced to lactic acid bacteria (Lactobacillus acidophilus). Now, the same group of researchers has found that the cause of ...
Cell & Microbiology
Feb 6, 2018
0
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