News tagged with journal of cell biology
Chemosensitivity of cancer cells depends on their protein dependency
Oct 26, 2009 |
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Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published ...
Researchers reveal mechanism for neuron self-preservation
Oct 19, 2009 |
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Tsuruta et al. find that a lipid kinase directs a voltage-gated calcium channel's degradation to save neurons from a lethal dose of overexcitement. The study appears in the October 19, 2009 issue of the Journal of ...
New study resolves the mysterious origin of Merkel cells
Sep 28, 2009 |
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A new study resolves a 130-year-old mystery over the developmental origin of specialized skin cells involved in touch sensation. The findings will appear in the October 5, 2009 issue of the Journal of Cell Bi ...
Landmark study sheds new light on human chromosomal birth defects
Sep 16, 2009 |
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Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular ...
Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases
Sep 14, 2009 |
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Li et al. explain how prolonged stress sparks the endoplasmic reticulum (ER) to release its calcium stores, inducing cells to undergo apoptosis in several aging-related diseases.The study will appear in the September 21, ...
Study shows how disruption of spectrin-actin network causes lens cells in the eye to lose shape
Sep 14, 2009 |
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A network of proteins underlying the plasma membrane keeps epithelial cells in shape and maintains their orderly hexagonal packing in the mouse lens, say Nowak et al. The study will appear in the September ...
Study reveals how a common virus eludes the immune system
Aug 31, 2009 |
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Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-m ...
Aurora B answers an XIST-ential question
Aug 24, 2009 |
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Early in development, mammalian female cells counteract their double dose of X chromosomes by coating one of them with a large RNA named XIST. The RNA binds to the same X chromosome from which it is transcribed ...
Scientists isolate protein that may be 'boon' to medicine
Aug 05, 2009 |
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Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." The findings are published in the August issue of the Journal of Cell Biology.
HIV uses autophagy for its own means
Medicine & Health / HIV & AIDS
Jul 27, 2009 |
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Not satisfied with simply thwarting its host's defensive maneuvers, HIV actually twists one to its advantage, based on new findings from Kyei et al. in the July 27, 2009 issue of the Journal of Cell Biology. Vojo D ...
Dynamic molecular mechanism to keep brain activity stable
Jul 13, 2009 |
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In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake ...
Building memories with actin
Jul 13, 2009 |
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Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, ...
Intestinal cells surprisingly active in pursuit of nutrition and defense
Jun 29, 2009 |
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Every cell lining the small intestine bristles with thousands of tightly packed microvilli that project into the gut lumen, forming a brush border that absorbs nutrients and protects the body from intestinal ...
How mitochondria get their membranes bent
Jun 24, 2009 |
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Underneath their smooth surface mitochondria harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities. Now researchers have identified two proteins ...
Heart saves muscle
May 25, 2009 |
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A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al. The findings will be published online on Monday, May 25, 2009 ...
