Journal of Clinical Investigation
hideThe Journal of Clinical Investigation (JCI or J Clin Invest) is a leading biomedical journal, with a 2008 impact factor of 16.559. The journal makes its research articles -- including access to articles back to 1924 -- freely available online.
The website of the journal describes it as "a premier venue for critical advances in biomedical research, authoritative reviews, and commentaries that place research articles in context." The first issue of the journal appeared in 1924, and within a few decades, it had established itself as a reputed journal for primary clinical research.
The JCI's Editorial Board is unique in that its members are located chiefly at a singular academic medical center and are predominantly members of the American Society for Clinical Investigation. The leadership of the Editorial Board changes every five years: As of March 2007, the Editorial Board is located at the University of Pennsylvania under the leadership of Laurence A. Turka, M.D. From March 2002 to March 2007, the Editorial Board was located at Columbia University under the leadership of Andrew Marks, M.D. Ushma S. Neill, formerly with Nature Medicine, is the journal's Executive Editor.
This monthly journal publishes original research and review articles, including periodic review series focusing on important topics in biomedicine.
For more information about Journal of Clinical Investigation, read the full article at
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News tagged with journal of clinical investigation
Tumors Feel the Deadly Sting of Nanobees
Nanotechnology / Bio & Medicine
Aug 28, 2009 |
4.8 / 5 (13) |
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When bees sting, they pump into their victims a peptide toxin called melittin that destroys cell membranes. Now, by encapsulating this extremely potent molecule within a nanoparticle, researchers at the Washington University ...
Experimental Approach May Reverse Rheumatoid Arthritis and Osteoporosis
Sep 21, 2009 |
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(PhysOrg.com) -- Researchers have identified a mechanism that may keep a well known signaling molecule from eroding bone and inflaming joints, according to an early study published online today in the Journal of Clinical In ...
Marijuana helps in battle against cancer: study
Apr 02, 2009 |
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The main chemical in marijuana appears to aid in the destruction of brain cancer cells, offering hope for future anti-cancer therapies, researchers in Spain wrote in a study released Thursday.
New way to kill cancer found using body's immune system
Jul 21, 2009 |
5 / 5 (9) |
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(PhysOrg.com) -- Scientists have discovered a new way of killing cancer cells in a breakthrough that could eventually lead to new treatments for a range of different cancers.
Breakthrough in the treatment of bacterial meningitis
May 13, 2009 |
5 / 5 (8) |
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It can take just hours after the symptoms appear for someone to die from bacterial meningitis. Now, after years of research, experts at The University of Nottingham have finally discovered how the deadly meningococcal bacteria ...
Ice cream may target the brain before your hips, study suggests
Sep 14, 2009 |
4.9 / 5 (8) |
2
Blame your brain for sabotaging your efforts to get back on track after splurging on an extra scoop of ice cream or that second burger during Friday night's football game.
Tumors feel the deadly sting of nanobees
Nanotechnology / Bio & Medicine
Aug 10, 2009 |
3.9 / 5 (7) |
0
(PhysOrg.com) -- When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at Washington University School of Medicine in St. Louis. The researchers ...
Scientists increases understanding of two types of blindness
Feb 07, 2009 |
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Though based on mouse studies, the research bolsters the idea that humans suffering from these and other eye conditions may be able to help preserve function by adding antioxidants to their diet, and explains why this would ...
Trojan horse for ovarian cancer -- nanoparticles turn immune system soldiers against tumor cells
Nanotechnology / Bio & Medicine
Jul 15, 2009 |
5 / 5 (5) |
1
In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor.
Biology of flushing could renew niacin as cholesterol drug
Apr 06, 2009 |
4.8 / 5 (4) |
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Deft molecular detective work at Duke University Medical Center suggests that scientists may soon be able to resurrect niacin as one of the best and cheapest ways to manage cholesterol.
Licorice compound offers new cancer prevention strategy
Mar 23, 2009 |
4.7 / 5 (3) |
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A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.
Research points to new target for stopping colon cancer
Aug 17, 2009 |
4.3 / 5 (3) |
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New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a ...
Engineered human fusion protein inhibits HIV-1 replication
Sep 08, 2009 |
5 / 5 (2) |
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In 2004, Jeremy Luban and colleagues from the University of Geneva, Switzerland, reported that New World owl monkeys (Aotus genus) make a fusion protein - AoT5Cyp - that potently blocks HIV-1 infection. The human genome encodes ...
Scientists discover cells that control inflammation in chronic disease
Nov 17, 2009 |
5 / 5 (2) |
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(PhysOrg.com) -- A new type of immune cell that can be out of control in certain chronic inflammatory diseases, worsening the symptoms of conditions like psoriasis and asthma, is described for the first time ...
Body's defenses may worsen chronic lung diseases in smokers
Feb 09, 2009 |
4.5 / 5 (2) |
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Although the immune system is designed to protect the body from harm, it may actually worsen one of the most difficult-to-treat respiratory diseases: chronic obstructive pulmonary disorder (COPD), according to new University ...
