Journal of Clinical Investigation

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The Journal of Clinical Investigation (JCI or J Clin Invest) is a leading biomedical journal, with a 2008 impact factor of 16.559. The journal makes its research articles -- including access to articles back to 1924 -- freely available online.

The website of the journal describes it as "a premier venue for critical advances in biomedical research, authoritative reviews, and commentaries that place research articles in context." The first issue of the journal appeared in 1924, and within a few decades, it had established itself as a reputed journal for primary clinical research.

The JCI's Editorial Board is unique in that its members are located chiefly at a singular academic medical center and are predominantly members of the American Society for Clinical Investigation. The leadership of the Editorial Board changes every five years: As of March 2007, the Editorial Board is located at the University of Pennsylvania under the leadership of Laurence A. Turka, M.D. From March 2002 to March 2007, the Editorial Board was located at Columbia University under the leadership of Andrew Marks, M.D. Ushma S. Neill, formerly with Nature Medicine, is the journal's Executive Editor.

This monthly journal publishes original research and review articles, including periodic review series focusing on important topics in biomedicine.

For more information about Journal of Clinical Investigation, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with journal of clinical investigation

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Ice cream may target the brain before your hips, study suggests

Ice cream may target the brain before your hips, study suggests

Medicine & Health / Research

created Sep 14, 2009 | popularity 4.9 / 5 (8) | comments 2

Blame your brain for sabotaging your efforts to get back on track after splurging on an extra scoop of ice cream or that second burger during Friday night's football game.


Tumors Feel the Deadly Sting of Nanobees

Nanotechnology / Bio & Medicine

created Aug 28, 2009 | popularity 4.8 / 5 (13) | comments 3

When bees sting, they pump into their victims a peptide toxin called melittin that destroys cell membranes. Now, by encapsulating this extremely potent molecule within a nanoparticle, researchers at the Washington University ...


New way to kill cancer found using body's immune system

Medicine & Health / Cancer

created Jul 21, 2009 | popularity 5 / 5 (9) | comments 6

(PhysOrg.com) -- Scientists have discovered a new way of killing cancer cells in a breakthrough that could eventually lead to new treatments for a range of different cancers.


Experimental Approach May Reverse Rheumatoid Arthritis and Osteoporosis

Medicine & Health / Research

created Sep 21, 2009 | popularity 4.8 / 5 (12) | comments 0

(PhysOrg.com) -- Researchers have identified a mechanism that may keep a well known signaling molecule from eroding bone and inflaming joints, according to an early study published online today in the Journal of Clinical In ...


Tumors feel the deadly sting of nanobees

Nanotechnology / Bio & Medicine

created Aug 10, 2009 | popularity 3.9 / 5 (7) | comments 0

(PhysOrg.com) -- When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at Washington University School of Medicine in St. Louis. The researchers ...


Trojan horse for ovarian cancer -- nanoparticles turn immune system soldiers against tumor cells

Nanotechnology / Bio & Medicine

created Jul 15, 2009 | popularity 5 / 5 (5) | comments 1

In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor.


Novel cancer gene accelerates or stops tumour growth

Medicine & Health / Cancer

created May 27, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Researchers at the Hospital for Sick Children (SickKids) and the University of Toronto have found a gene that plays a crucial role in the development of rhabdomyosarcoma - the most common childhood sarcoma ...


Breakthrough in the treatment of bacterial meningitis

Medicine & Health / Research

created May 13, 2009 | popularity 5 / 5 (8) | comments 0

It can take just hours after the symptoms appear for someone to die from bacterial meningitis. Now, after years of research, experts at The University of Nottingham have finally discovered how the deadly meningococcal bacteria ...


Biology of flushing could renew niacin as cholesterol drug

Medicine & Health / Research

created Apr 06, 2009 | popularity 4.8 / 5 (4) | comments 1

Deft molecular detective work at Duke University Medical Center suggests that scientists may soon be able to resurrect niacin as one of the best and cheapest ways to manage cholesterol.


Marijuana helps in battle against cancer: study

Medicine & Health / Cancer

created Apr 02, 2009 | popularity 5 / 5 (11) | comments 4

The main chemical in marijuana appears to aid in the destruction of brain cancer cells, offering hope for future anti-cancer therapies, researchers in Spain wrote in a study released Thursday.


Licorice compound offers new cancer prevention strategy

Medicine & Health / Cancer

created Mar 23, 2009 | popularity 4.7 / 5 (3) | comments 1

A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.


Scientists discover cells that control inflammation in chronic disease

Scientists discover cells that control inflammation in chronic disease

Medicine & Health / Research

created Nov 17, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- A new type of immune cell that can be out of control in certain chronic inflammatory diseases, worsening the symptoms of conditions like psoriasis and asthma, is described for the first time ...


Researchers find inflammation critical in aortic dissection

Medicine & Health / Research

created Nov 16, 2009 | popularity not rated yet | comments 0

The aorta, the body's largest artery, stretches from the chest to below the kidneys, expanding and contracting with the pressure of blood driven directly into it by the heart. Although its walls are extraordinarily strong, ...


Wistar researchers show targeting 'normal' cells in tumors slows growth

Medicine & Health / Cancer

created Nov 16, 2009 | popularity 1 / 5 (1) | comments 0

Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.


Study provides first clear idea of how rare bone disease progresses

Study provides first clear idea of how rare bone disease progresses

Medicine & Health / Research

created Nov 12, 2009 | popularity 5 / 5 (1) | comments 0

An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ...