Researchers identify female sex determining gene in mice

Researchers at the Francis Crick Institute and the Université Cote d'Azur, together with other labs in France and Switzerland, have identified a gene which is an early determining factor of ovary development in mice.

Nano-sized carbon material could be used to treat Down syndrome

Scientists at the Texas A&M University Health Science Center (Texas A&M Health) have discovered that a nano-sized carbon material derived from the oxidation of carbon-rich sources could be used to treat Down syndrome and ...

PFAS found in blood of dogs, horses living near Fayetteville, NC

In a new study, researchers from North Carolina State University detected elevated PFAS levels in the blood of pet dogs and horses from Gray's Creek, N.C.—including dogs that only drank bottled water. The work establishes ...

A key step toward growing human kidneys in the laboratory

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world. Being able to grow working kidney tissue in a laboratory could help accelerate medical treatments ...

page 1 from 3

Renal function

Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result (eGFR and eCCr).

The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).

It is commonly believed to be the amount of liquid filtered out of the blood that gets processed by the kidneys. Physiologically, these quantities (volumetric blood flow and mass removal) are only related loosely.

This text uses material from Wikipedia, licensed under CC BY-SA