Related topics: kidney disease , kidney , kidney failure , chronic kidney disease , journal of the american society of nephrology



Renal function

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Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result (eGFR and eCCr).

The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).

It is commonly believed to be the amount of liquid filtered out of the blood that gets processed by the kidneys. Physiologically, these quantities (volumetric blood flow and mass removal) are only related loosely.

For more information about Renal function, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with kidney function

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Reduced kidney function, high levels of protein in urine associated with adverse outcomes

Medicine & Health / Diseases

created Feb 02, 2010 | popularity 5 / 5 (1) | comments 0

Patients with high levels of proteinuria (protein in urine) in addition to another marker of reduced kidney function had an associated increased risk of all-cause death, heart attack or progression to kidney failure, according ...


Biochemists Provide New Key for Treating Fabry Disease, a Rare Childhood Disorder

Chemistry / Biochemistry

created Feb 02, 2010 | popularity not rated yet | comments 0 | with audio podcast

(PhysOrg.com) -- A research team led by biochemist Scott Garman at the University of Massachusetts Amherst has for the first time determined the mechanism of one of the cell’s 'recycling' enzymes, human alpha-galactosidase ...


'Silent strokes' linked to kidney failure in diabetics

Medicine & Health / Diseases

created Jan 28, 2010 | popularity 4.5 / 5 (2) | comments 0

In patients with type 2 diabetes, silent cerebral infarction (SCI) -- small areas of brain damage caused by injury to small blood vessels -- signals an increased risk of progressive kidney disease and kidney failure, according ...


Even mild kidney disease harms a child's quality of life

Medicine & Health / Diseases

created Jan 27, 2010 | popularity not rated yet | comments 0

Challenging prevailing wisdom that only children with end-stage kidney disease suffer physical, social, emotional and educational setbacks from their disease, research led by Johns Hopkins Children's Center shows that even ...


Small amounts of lead may damage children's kidneys

Medicine & Health / Health

created Jan 11, 2010 | popularity 5 / 5 (1) | comments 0

Small amounts of lead in the bodies of healthy children and teens — amounts well below the levels defined as "concerning" by the U.S. Centers for Disease Control and Prevention (CDC) — may worsen kidney function, according ...


Abnormal blood calcium levels deadly for kidney disease patients

Medicine & Health / Diseases

created Jan 07, 2010 | popularity 4 / 5 (1) | comments 0

Abnormally high or low blood calcium levels are linked to an increased chance of premature death in non-dialysis kidney disease patients, according to a study appearing in an upcoming issue of the Clinical Journal of the Am ...


Kidney injury in hospital increases long-term risk of death

Medicine & Health / Diseases

created Dec 17, 2009 | popularity not rated yet | comments 0

Patients with sudden loss of kidney function, called acute kidney injury (AKI), are more likely to die prematurely after leaving the hospital—even if their kidney function has apparently recovered, according to an upcoming ...


Hospital re-admission high for dialysis patients treated in long-term care hospitals

Medicine & Health / Diseases

created Dec 14, 2009 | popularity not rated yet | comments 0

A new study by University of Cincinnati (UC) nephrologists shows that most dialysis patients admitted to long-term care hospitals face readmission to acute care facilities, and those with acute kidney failure don't often ...


Gas improves blood flow and organ status during minimally invasive surgery

Medicine & Health / Research

created Dec 14, 2009 | popularity not rated yet | comments 0

As good as laparoscopy is in preventing some of the stresses of open surgery on the body, it does have drawbacks, including reduced blood flow and organ dysfunction. Laparoscopy is a type of surgery in the abdomen done through ...


Kidney disease patients benefit from surgery to prevent stroke

Medicine & Health / Diseases

created Dec 10, 2009 | popularity 5 / 5 (1) | comments 0

Physicians should be comfortable referring some patients with chronic kidney disease (CKD) for effective stroke prevention surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of ...


Epilepsy Drug Shows Promise in Treating Kidney Disease

Medicine & Health / Medications

created Dec 03, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- An anti-convulsant drug commonly used to treat epilepsy reduces cysts in mice that are associated with polycystic kidney disease (PKD), a difficult to treat ailment that afflicts 600,000 people in the United ...


Heart failure patients with kidney dysfunction don't recover well after hospital discharge

Medicine & Health / Diseases

created Nov 18, 2009 | popularity not rated yet | comments 0

Most heart failure patients who develop kidney failure in the hospital do not recover from it before going home and are at increased risk of either being re-hospitalized or dying within the year, according to a Henry Ford ...


Kidney function decline increases risk of heart failure and premature death

Medicine & Health / Diseases

created Nov 05, 2009 | popularity not rated yet | comments 0

Declining kidney function is linked to a higher risk of heart failure, heart attack, peripheral arterial disease, and early death in individuals with or without kidney disease, according to a pair of studies appearing in ...


Can charcoal fight heart disease in kidney patients?

Medicine & Health / Diseases

created Nov 02, 2009 | popularity not rated yet | comments 0

Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual ...


Women with chronic kidney disease more likely than men to go undiagnosed

Medicine & Health / Diseases

created Nov 01, 2009 | popularity not rated yet | comments 0

Woman are at particular risk of their primary care physicians delaying diagnosis of chronic kidney disease (CKD), according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific ...