News tagged with knockout mice
Scientists link dietary DHA to male fertility
Who knew that male fertility depends on sperm-cell architecture? A University of Illinois study reports that a certain omega-3 fatty acid is necessary to construct the arch that turns a round, immature sperm cell into a pointy-headed ...
Jan 09, 2012 |
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New insights into insulin resistance could lead to better drugs for diabetics
Research published in the October Molecular and Cellular Biology moves us closer to developing drugs that could mitigate diabetes.
Oct 21, 2011 |
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Intestinal protein may have role in ADHD, other neurological disorders
A biochemical pathway long associated with diarrhea and intestinal function may provide a new therapeutic target for treating ADHD (Attention Deficit Hyperactivity Disorder) other neuropsychiatric disorders, according to ...
Aug 11, 2011 |
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New resource to unlock the role of microRNAs
A new resource to define the roles of microRNAs is announced today in Nature Biotechnology. The resource, called mirKO, gives researchers access to tools to investigate the biological role and significance for human health ...
Aug 07, 2011 |
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Gene gives clues to self-injurious behavior in rare disorder
In humans, inherited mutations in a gene called HPRT1 lead to very specific self-destructive behavior. Boys with Lesch-Nyhan disease experience uncontrollable urges to bite their fingers, slam their arms into doorways and ...
Jul 27, 2011 |
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Research sheds new light on how blood clots form
Scripps Research Institute scientists have discovered new elements of the blood clot-formation process. The findings could lead to better drugs for preventing heart attacks and other clot-related conditions.
Jun 13, 2011 |
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Research team tests alternative approach to treating diabetes
In a mouse study, scientists at Mayo Clinic Florida have demonstrated the feasibility of a promising new strategy for treating human type 2 diabetes, which affects more than 200 million people worldwide.
Jun 09, 2011 |
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Stem cell treatment may offer option for broken bones that don't heal
Researchers at the University of North Carolina at Chapel Hill School of Medicine have shown in an animal study that transplantation of adult stem cells enriched with a bone-regenerating hormone can help mend bone fractures ...
Jun 05, 2011 |
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Abcc10 may be effective in extending the effectiveness of anticancer drugs
Today's anticancer drugs often work wonders against malignancies, but sometimes tumors become resistant to the effects of such drugs, and treatment fails. Medical researchers would like to find ways of counteracting such ...
May 16, 2011 |
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Can one model the social deficits of autism and schizophrenia in animals?
5 May 2011 - The use of animal models to study human disease is essential to help advance our understanding of disease and to develop new therapeutic treatments.
Medicine & Health / Psychology & Psychiatry
May 05, 2011 |
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New genetic deafness syndrome identified
Ten years ago, scientists seeking to understand how a certain type of feature on a cell called an L-type calcium channel worked created a knockout mouse missing both copies of the CACNA1D gene.
Mar 09, 2011 |
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A mental retardation gene provides insights into brain formation (w/ Video)
(PhysOrg.com) -- Scientists at Duke University Medical Center have uncovered clues to memory and learning by exploring the function of a single gene that governs how neurons form new connections. The finding may also provide ...
Medicine & Health / Neuroscience
Feb 15, 2011 |
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Deleting ghrelin receptor, but not ghrelin, turns up fat-burning thermostat
Deleting the receptor, not the protein ghrelin itself, turns up the body's fat-burning thermostat, giving aging mice an exothermic boost toward a svelte physique, researchers reported at the American Society of Cell Biology's ...
Dec 13, 2010 |
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Study reveals capsaicin can act as cocarcinogen
The September cover story of the nation's leading cancer journal, Cancer Research, features a new study from The Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer ...
Sep 02, 2010 |
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Muscle gene may provide new treatments for obesity and diabetes
(PhysOrg.com) -- Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal ...
Jul 27, 2010 |
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