News tagged with knockout mice
Enhanced sweet taste: This is your tongue on pot
Dec 22, 2009 |
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New findings from the Monell Center and Kyushu University in Japan report that endocannabinoids act directly on taste receptors on the tongue to enhance sweet taste.
Up a little on the left... now, over to the right... Scientists find a source of nonallergic itch
Dec 22, 2009 |
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Scratching below the surface of a troublesome sensation that's equal parts tingle-tickle-prickle, sensory scientists from Johns Hopkins have discovered in mice a molecular basis for nonallergic itch.
Gene knockout may cheer up mice
Medicine & Health / Neuroscience
Nov 12, 2009 |
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Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to the PKCI/HINT1 knocko ...
Researchers have immune cells running in circles
Nov 02, 2009 |
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(PhysOrg.com) -- University of Illinois at Chicago College of Medicine researchers have identified the important role a protein plays in the body's first line of defense in directing immune cells called neutrophils toward ...
Th17 cells summon an immune system strike against cancer (w/ Video)
Oct 29, 2009 |
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A specific type of T helper cell awakens the immune system to the stealthy threat of cancer and triggers an attack of killer T cells custom-made to destroy the tumors, scientists from The University of Texas M. D. Anderson ...
Protein critical for insulin secretion may be contributor to diabetes
Oct 26, 2009 |
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A cellular protein from a family involved in several human diseases is crucial for the proper production and release of insulin, new research has found, suggesting that the protein might play a role in diabetes.
NEDD9 protein supports growth of aggressive breast cancer
Oct 02, 2009 |
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Researchers at Fox Chase Cancer Center have demonstrated that a protein called NEDD9 may be required for some of the most aggressive forms of breast cancer to grow. Their findings, based on the study of a mouse model of breast ...
Longer-lived, healthier mice offer promise of drug treatments for age-related diseases
Oct 01, 2009 |
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Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics ...
Genetically engineered mice yield clues to 'knocking out' cancer
Jul 01, 2009 |
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Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. ...
Persistent bacterial infection exploits killing machinery of immune cells
Nov 02, 2008 |
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A new study reveals an important and newly discovered pathway used by disease-causing bacteria to evade the host immune system and survive and grow within the very cells meant to destroy them. This discovery may lead to new ...
