Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...
Biotechnology
May 1, 2015
0
35
The proteins that underlie nearly all biological mechanisms are produced from RNA molecules transcribed from genetic sequences in DNA. However, a large proportion of transcribed RNA is not transcoded into proteins and appears ...
Cell & Microbiology
Jan 9, 2015
0
52
What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...
Biotechnology
Apr 2, 2013
0
0
Cyclin-dependent kinase 1 (Cdk1) is a member of the Cdk family of enzymes which control the cell cycle. Philipp Kaldis at the A*STAR Institute of Molecular and Cell Biology and co-workers have now shown that Cdk1 plays a ...
Cell & Microbiology
Jun 20, 2012
0
0
Research published in the October Molecular and Cellular Biology moves us closer to developing drugs that could mitigate diabetes.
Cell & Microbiology
Oct 21, 2011
0
1
Deleting the receptor, not the protein ghrelin itself, turns up the body's fat-burning thermostat, giving aging mice an exothermic boost toward a svelte physique, researchers reported at the American Society of Cell Biology's ...
Cell & Microbiology
Dec 13, 2010
0
0
(PhysOrg.com) -- Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal ...
Biochemistry
Jul 27, 2010
0
0
The mammalian fucose mutarotase enzyme is known to be involved in incorporating the sugar fucose into protein. Female mice that lack the fucose mutarotase (FucM) gene refuse to let males mount them, and will attempt copulation ...
Biotechnology
Jul 8, 2010
0
0
Knocking genes out of action allows researchers to learn what genes do by seeing what goes wrong without them. University of Utah biologists pioneered the field. Mario Capecchi won a Nobel Prize for developing knockout mice. ...
Biotechnology
Apr 25, 2010
0
0
Scientists have proved experimentally what has been suspected since the discovery of Merkel cells in the skin over a century ago: the sense of light touch that is critical for hand dexterity would not be possible without ...
Cell & Microbiology
Dec 8, 2009
0
0
