Lab-on-a-chip
hideA lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single chip of only millimeters to a few square centimeters in size. LOCs deal with the handling of extremely small fluid volumes down to less than pico liters. Lab-on-a-chip devices are a subset of MEMS devices and often indicated by "Micro Total Analysis Systems" (µTAS) as well. Microfluidics is a broader term that describes also mechanical flow control devices like pumps and valves or sensors like flowmeters and viscometers. However, strictly regarded "Lab-on-a-Chip" indicates generally the scaling of single or multiple lab processes down to chip-format, whereas "µTAS" is dedicated to the integration of the total sequence of lab processes to perform chemical analysis. The term "Lab-on-a-Chip" was introduced later on when it turned out that µTAS technologies were more widely applicable than only for analysis purposes.
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News tagged with lab on a chip
'No muss, no fuss' miniaturized analysis for complex samples developed
Chemistry / Analytical Chemistry
Nov 18, 2009 |
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The goal of an integrated, miniaturized laboratory analysis system, also known as a "lab-on-a-chip," is simple: sample in, answer out. However, researchers wanting to use these microfluidic devices to analyze ...
Sensor biochips could aid in cancer diagnosis and treatment
Chemistry / Analytical Chemistry
Oct 22, 2009 |
5 / 5 (1) |
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It is very difficult to predict whether a cancer drug will help an individual patient: only around one third of drugs will work directly in a given patient. Researchers at the Heinz Nixdorf Chair for Medical ...
Researchers develop new lab-on-a-chip technique
Oct 07, 2009 |
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Scientists at the University of Toronto have developed a new "lab-on-a-chip" technique that analyses tiny samples of blood and breast tissue to identify women at risk of breast cancer much more quickly than ever before.
Lab-on-a-Chip Performs 1,000 Chemical Reactions At Once
Chemistry / Analytical Chemistry
Sep 27, 2009 |
4.9 / 5 (7) |
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Flasks, beakers, and hot plates may soon be a thing of the past in medicinal chemistry labs. Instead of handling a few experiments on a benchtop, scientists may simply pop a microchip into a computer and instantly run thousands ...
LEGO toy helps researchers learn what happens on nanoscale
Aug 25, 2009 |
4.2 / 5 (10) |
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Johns Hopkins engineers are using a popular children's toy to visualize the behavior of particles, cells and molecules in environments too small to see with the naked eye. These researchers are arranging little ...
New microchip technology performs 1,000 chemical reactions at once
Chemistry / Analytical Chemistry
Aug 03, 2009 |
5 / 5 (11) |
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(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer ...
'Microfluidic Palette' May Paint Clearer Picture of Biological Processes
Jul 28, 2009 |
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(PhysOrg.com) -- The masterpieces that spring from the talents of Rembrandt, Van Gogh and other artists often begin with the creation of a gradient of colors on a palette. In a similar manner, researchers ...
Optical chip detects blood molecules
Chemistry / Analytical Chemistry
Jul 15, 2009 |
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(PhysOrg.com) -- A portable 'lab on a chip' that can identify target molecules in blood samples has been created by European researchers. It is being used to measure fertility hormones and detect the genes ...
Stirred, not shaken: Bio-inspired cilia mix medical reagents at small scales
Jun 30, 2009 |
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The equipment used for biomedical research is shrinking, but the physical properties of the fluids under investigation are not changing. This creates a problem: the reservoirs that hold the liquid are now ...
Liquid lens creates tiny flexible laser on a chip
May 11, 2009 |
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(PhysOrg.com) -- Like tiny Jedi knights, tunable fluidic micro lenses can focus and direct light at will to count cells, evaluate molecules or create on-chip optical tweezers, according to a team of Penn State engineers. ...
Researchers Develop 'Lab on a Tube' Monitoring Device
May 04, 2009 |
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(PhysOrg.com) -- The need for improved monitoring of neurotrauma patients has resulted in the development of a prototype of a novel, multitasking “lab on a tube” at the University of Cincinnati (UC).
Chip simulates metabolism of medicine in human body
Chemistry / Analytical Chemistry
Apr 24, 2009 |
5 / 5 (5) |
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(PhysOrg.com) -- A tiny electrochemical cell, developed by researchers of the MESA+ Institute for Nanotechnology, The Netherlands, is able to mimick the behaviour of medicine inside a human body. This chip ...
Micromagnetic-microfluidic device could quickly pull pathogens from the bloodstream
Mar 25, 2009 |
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Sepsis, an infection of the blood, can quickly overwhelm the body's defenses and is responsible for more than 200,000 deaths per year in the U.S. alone. Premature newborns and people with weakened immune systems are especially ...
Lab-on-a-chip hones in on how cancer cells break free
Mar 18, 2009 |
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Johns Hopkins engineers have invented a method that could be used to help figure out how cancer cells break free from neighboring tissue, an "escape" that can spread the disease to other parts of the body. ...
Portable kit may one day detect plant disease before disastrous outbreak
Feb 23, 2009 |
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This science may literally be outside the box: A briefcase-sized kit is carried to a field where thousands of tons of food are growing. The search is for microorganisms that could infect and kill the plants, wreaking havoc ...
