News tagged with leukemic cells
A leukemia drug kills cancerous T-cells while sparing normal immunity
Leukemic cutaneous T-cell lymphoma (L-CTCL) is a leukemia arising from T-cells, a type of white blood cell. This cancer can involve the skin and other organs, and patients often die within three years.
Jan 25, 2012 |
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'PARP' drug sabotages DNA repair in pre-leukemic cells
Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits ...
Dec 12, 2011 |
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Study reveals no impact of age on outcome in chronic myeloid leukemia patients treated with imatinib
While the median age at diagnosis for chronic myeloid leukemia (CML) is over 60 years old and incidence increases dramatically with age,limited data are available about the long-term outcome for older patients treated with i ...
Mar 30, 2011 |
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Scientists find key pathway implicated in progression of childhood cancer
A protein crucial for the immune response appears to be a key player in the progression of a devastating form of childhood leukemia called T-cell acute lymphoblastic leukemia (T-ALL). Suppressing the activity of the protein ...
Sep 13, 2010 |
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Researchers say vaccine appears to 'mop up' leukemia cells Gleevec leaves behind
Johns Hopkins Kimmel Cancer Center researchers say preliminary studies show that a vaccine made with leukemia cells may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) ...
Jan 07, 2010 |
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Protein linked to leukemia 'bookmarks' highly active genes during cell division
Each cell inherits genes from its parent as well as epigenetic information - what amounts to an instruction manual that specifies which genes should be activated or "expressed," when and to what level. Cold Spring Harbor ...
Jan 05, 2010 |
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New tools for prediction of disease progression in acute childhood leukemia
(PhysOrg.com) -- Researchers at Uppsala University and University Children’s Hospital in Uppsala have devised powerful new tools for typing cells from children with acute lymphatic leukemia and for prediction of how children ...
Nov 27, 2009 |
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Key found to how tumor cells invade the brain in childhood cancer
Despite great strides in treating childhood leukemia, a form of the disease called T-cell acute lymphoblastic leukemia (T-ALL) poses special challenges because of the high risk of leukemic cells invading ...
Jun 17, 2009 |
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Mutant genes in high-risk childhood leukemias identified
A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death. The finding suggests specific drugs that could ...
May 19, 2009 |
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Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharma ...
Mar 26, 2009 |
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Study finds more than 100 gene variations linked with response to leukemia treatment
Scientists from St. Jude Children's Research Hospital and the Children's Oncology Group (COG) have discovered in children with acute lymphoblastic leukemia (ALL) scores of inherited genetic variations that clinicians might ...
Jan 27, 2009 |
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