News tagged with ligand
A silver bullet to beat cancer?
The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects.
Feb 02, 2012 |
5 / 5 (3) |
0
|
Avoid the fallout: New ligands for nuclear waste treatment
(PhysOrg.com) -- Storage and containment of the "nuclear legacy", the highly radiotoxic residues from spent nuclear reactors is a pressing problem for the nuclear power industry that must be solved if nuclear ...
Jan 24, 2012 |
not rated yet |
1
Possible new pathway can overcome glioblastoma resistance
Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months.
Jan 24, 2012 |
5 / 5 (1) |
0
Scientists paint new picture of dance between protein and binding partners
Using a blend of technologies, scientists from the Florida campus of The Scripps Research Institute have painted a new picture of how biochemical information can be transmitted through the modification of a protein. Previously, ...
Jan 10, 2012 |
5 / 5 (2) |
0
|
Nanotechnology researchers develop new strategy to deliver chemotherapy to prostate cancer cells
Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater ...
Nanotechnology / Bio & Medicine
Jan 09, 2012 |
5 / 5 (4) |
0
|
A gene that protects against colorectal cancers
The research team in France has developed an animal model carrying a mutation of the DCC gene. Mice carrying the mutation develop tumours, because this gene can no longer induce the death of the cancer cells. This discovery ...
Dec 14, 2011 |
not rated yet |
0
Nanocrystals go bare: Stripping material’s tiny tethers
(PhysOrg.com) -- Researchers with the DOE's Lawrence Berkeley National Laboratory have discovered a universal technique for stripping nanocrystals of tether-like molecules that until now have posed as obstacles ...
Nanotechnology / Nanomaterials
Dec 09, 2011 |
5 / 5 (3) |
0
|
In new quantum-dot LED design, researchers turn troublesome molecules to their advantage
By nestling quantum dots in an insulating egg-crate structure, researchers at the Harvard School of Engineering and Applied Sciences (SEAS) have demonstrated a robust new architecture for quantum-dot light-emitting devices ...
Nov 15, 2011 |
5 / 5 (4) |
1
|
Chemists reveal the force within you
A new method for visualizing mechanical forces on the surface of a cell, reported in Nature Methods, provides the first detailed view of those forces, as they occur in real-time.
Nov 09, 2011 |
4 / 5 (2) |
4
|
Bidentate chelates with larger spacers: Chelating Lewis acids prepared by double hydroalumination of dialkynylsilanes
(PhysOrg.com) -- Molecular oligoacceptors (chelating Lewis acids) are interesting compounds that are potentially applicable in phase-transfer processes, catalysis, or molecular recognition. Compounds with ...
Nov 08, 2011 |
5 / 5 (1) |
3
Researchers help in search for new ways to image, therapeutically target melanoma
Because the incidence of malignant melanoma is rising faster than any other cancer in the U.S., researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues at Tampa-based Intezyne Technologies, Inc., Western Carolina ...
Nov 03, 2011 |
not rated yet |
0
Do deficits in brain cannabinoids contribute to eating disorders?
A new report in Biological Psychiatry suggests that deficits in endocannabinoid function may contribute to anorexia nervosa and bulimia. Endocannabinoids are substances made by the brain that affect brain function and ch ...
Medicine & Health / Psychology & Psychiatry
Oct 31, 2011 |
5 / 5 (1) |
0
Folate receptors may serve as a front door to ovarian cancer treatment
A new strategy that takes advantage of ovarian cancer's reliance on folate appears to give relapse patients extra months of life with few side effects, researchers say.
Oct 28, 2011 |
5 / 5 (1) |
0
|
A better target for B-cell lymphomas: From a library of MAG antagonists to nanomolar CD22 ligands
Patients suffering from B-cell lymphomas can be treated with antibodies directed against the B-lymphocyte antigen CD20.
Oct 25, 2011 |
not rated yet |
0
|
Oxygen inactivates the enzyme function in three phases: study
Scientists from the Faculty of Biology and Biotechnology at the RUB have published a report in the Journal of Biological Chemistry explaining why enzymes used for the production of hydrogen are so sensitive to oxygen. In col ...
Oct 12, 2011 |
not rated yet |
0
Ligand
In coordination chemistry, a ligand is an ion or molecule (see also: functional group) that binds to a central metal atom to form a coordination complex. The bonding between metal and ligand generally involves formal donation of one or more of the ligand's electron pairs. The nature of metal-ligand bonding can range from covalent to ionic. Furthermore, the metal-ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known involving Lewis acidic "ligands."
Metal and metalloids are bound to ligands in virtually all circumstances, although gaseous "naked" metal ions can be generated in high vacuum. Ligands in a complex dictate the reactivity of the central atom, including ligand substitution rates, the reactivity of the ligands themselves, and redox. Ligand selection is a critical consideration in many practical areas, including bioinorganic and medicinal chemistry, homogeneous catalysis, and environmental chemistry.
Ligands are classified in many ways: their charge, their size (bulk), the identity of the coordinating atom(s), and the number of electrons donated to the metal (denticity or hapticity). The size of a ligand is indicated by its cone angle.
For more information about Ligand, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
