PON1 (paraoxonase 1), an enzyme associated with high-density lipoprotein (HDL), breaks down lipid peroxides, highly reactive fatty molecules that can damage blood vessels.
Biochemistry
Aug 20, 2021
0
288
Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a "stealthy" role in the progression of infection by reducing the immune response.
Molecular & Computational biology
Jul 12, 2021
0
140
Humans with a high cholesterol fear the "bad cholesterol"—the so-called low-density lipoprotein (LDL)—because it is genetic and cannot be regulated with medication. However, a healthy occurrence of LDL is important for ...
Molecular & Computational biology
Oct 8, 2020
0
4
Foxtail millet is an annual grass grown widely as a cereal crop in parts of India, China and Southeast Asia. Milling the grain removes the hard outer layer, or bran, from the rest of the seed. Now, researchers have identified ...
Biochemistry
Jan 22, 2020
1
11
University of Delaware researchers have discovered that lipoprotein lipase, an enzyme crucial for fat metabolism, may be contributing to wooden breast syndrome in broiler chickens.
Veterinary medicine
Nov 21, 2019
0
5
Scientists have improved their understanding of a new form of cell-cell communication that is based on extracellular RNA (exRNA). RNA, a molecule that was thought to only exist inside cells, now is known to also exist outside ...
Cell & Microbiology
Apr 4, 2019
1
400
After decades of work with no success, researchers have determined the high-resolution, three-dimensional structure for lipoprotein lipase, the enzyme that processes fats, or triglycerides, in the bloodstream and releases ...
Biochemistry
Feb 26, 2019
0
18
Why some biopharmaceuticals have a longer shelf life than others is a problem that has baffled scientists and manufacturers alike. Even the same medication, produced by different manufacturers, can vary in its storage life.
Biochemistry
Sep 28, 2018
0
10
Efforts to explore the landscape of small RNAs (sRNAs)—short RNA molecules that are poorly understood—often use high-throughput sequencing (sRNA-seq). These efforts are hampered by a lack of tools to identify, quantify ...
Biotechnology
Sep 7, 2018
0
3
High-density lipoprotein (HDL) is widely thought to protect against the development of atherosclerosis, yet drugs that raise levels of HDL cholesterol (HDL-C) have failed to reduce the risk of heart disease.
Biochemistry
Jul 2, 2018
0
8
A lipoprotein is a biochemical assembly that contains both proteins and lipids water-bound to the proteins. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins. Examples include the high-density (HDL) and low-density (LDL) lipoproteins, which enable fats to be carried in the blood stream, the transmembrane proteins of the mitochondrion and the chloroplast, and bacterial lipoproteins.
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