News tagged with lis1 gene
Researchers restore missing protein in rare genetic brain disorder
UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, ...
Sep 06, 2009 |
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Scientists show extra copies of a gene carry extra risk
Is more of a good thing better? A gene known as LIS1 is crucial for ensuring the proper placement of neurons in the developing brain. When an LIS1 gene is missing, brains fail to develop the characteristic folds; babies with ...
Feb 04, 2009 |
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From wimp to jock: How a cell motor gets pushy
A University of Utah researcher helped discover how a "wimpy" protein motor works with two other proteins to gain the strength necessary to move nerve cells and components inside them. The findings shed light ...
Apr 15, 2010 |
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Key factor in brain development revealed, offers insight into disorder
In the earliest days of brain development, the brain’s first cells – neuroepithelial stem cells -- divide continuously, producing a population of cells that eventually evolves into the various cells of the fully formed brain. ...
Mar 26, 2008 |
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Scientists Peer Into Stem Cells in Live Brain
Columbia University Medical Center scientists report they have observed the detailed sub-cellular behavior of neuronal precursor cells in living rat brain tissue.
Jul 11, 2007 |
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List of search results for lis1 gene