Related topics: cells
Hepatocyte
hideHepatocytes make up 70-80% of the cytoplasmic mass of the liver. These cells are involved in protein synthesis, protein storage and transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances. The hepatocyte also initiates the formation and secretion of bile.
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News tagged with liver cells
Old diabetes drug teaches experts new tricks
May 14, 2009 |
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Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood ...
New steps forward in cell reprogramming
Aug 10, 2009 |
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(PhysOrg.com) -- Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital (MGH) have substantially improved the odds of successfully reprogramming differentiated cells into induced ...
A breath of fresh air could improve drug toxicity screening
Sep 02, 2009 |
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A team led by Massachusetts General Hospital (MGH) researchers has developed an innovative way to culture liver cells for drug toxicity screening. In a report to be published in Proceedings of the National Academy of Sc ...
Stem cells crucial to diabetes cure in mice
Mar 16, 2009 |
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More than five years ago, Dr. Lawrence C.B. Chan and colleagues in his Baylor College of Medicine laboratory cured mice with type 1 diabetes by using a gene to induce liver cells to make insulin.
Researchers engineer metabolic pathway in mice to prevent diet-induced obesity
Jun 02, 2009 |
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In recent years, obesity has taken on epidemic proportions in developed nations, contributing significantly to major medical problems, early death and rising health care costs. According to Centers for Disease Control and ...
Discovery could lead to a new animal model for hepatitis C
Jan 28, 2009 |
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During its career, the potentially fatal hepatitis C virus has banked its success on a rather unusual strategy: its limitations. Its inability to infect animals other than humans and chimpanzees has severely ...
Transplanted Liver Cells Hold Hope for Treating Inherited Diseases
Oct 09, 2009 |
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(PhysOrg.com) -- Mike Gibson, chair of the Department of Biological Sciences at Michigan Technological University, has spent most of his professional life trying to better understand genetic metabolic disorders ...
New strategy for inhibiting virus replication
Aug 14, 2009 |
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Viruses need living cells for replication and production of virus progeny. Thus far, antiviral therapy primarily targets viral factors but often induces therapy resistance. New improved therapies attempt to targets cellular ...
Antifibrotic effects of green tea
Nov 18, 2009 |
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Several studies have shown that lipid peroxidation stimulates collagen production in fibroblasts and hepatic stellate cells (HSC), and plays an important role in the development of liver fibrosis. Hepatoprotective effects ...
Researchers identify genes linked to chemoresistance
Jul 20, 2009 |
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Two genes may contribute to chemotherapy resistance in drugs like 5-fluorouracil, which is used in liver cancer treatment, according to Virginia Commonwealth University Massey Cancer Center researchers.
Critical link in cell death pathway revealed
Jul 22, 2009 |
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The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are ...
Model tissue system reveals cellular communication via amino acids
Apr 03, 2009 |
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A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has found the first evidence of cell-to-cell communication by amino acids, the building blocks of proteins, rather ...
Suppressing cancer with a master control gene
Feb 23, 2009 |
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Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. Reciprocally, switching off the gene ...
Building the right cells
Biology /
Jan 04, 2009 |
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Just after 5 p.m. doors rattle shut and feet begin to shuffle past the narrow lab where Karim Si-Tayeb sits hunched over a microscope, all but invisible to the scientists leaving the Medical College of Wisconsin. Si-Tayeb ...
Old stain in a new combination
May 20, 2009 |
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New combinations of agents based on the oldest synthetic malaria drug, the methylene blue stain, can curb the spread of malaria parasites and make a significant contribution to the long-term eradication called for by the ...
