Longevity gene from naked mole rats extends lifespan of mice

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan.

The secret to a longer lifespan? Gene regulation holds a clue

Natural selection has produced mammals that age at dramatically different rates. Take, for example, naked mole rats and mice; the former can live up to 41 years, nearly ten times as long as similar-size rodents such as mice.

Scientists find longevity biomarkers

An international group of scientists studied the effects of 17 lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal ...

Living longer, not healthier

A study of long-lived mutant C. elegans by scientists at the University of Massachusetts Medical School shows that the genetically altered worms spend a greater portion of their life in a frail state and exhibit less activity ...

Reproduction and life span are intertwined

The gonad is well known to be important for reproduction but also affects animal life span. Removal of germ cells – the sperm and egg producing cells – increases longevity of the roundworm Caenorhabditis elegans. However, ...

Mice with fewer insulin-signaling receptors don't live longer

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...

The Secrets of Longevity

(PhysOrg.com) -- A complex network of genes, in combination with a low-calorie diet and exercise, appears to be a key factor in a long life expectancy. Professor Johan Auwerx’s team has published an article on this topic ...

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