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Lung cancer
hideLung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women (after breast cancer), is responsible for 1.3 million deaths worldwide annually. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.
The main types of lung cancer are small cell lung carcinoma and non-small cell lung carcinoma. This distinction is important, because the treatment varies; non-small cell lung carcinoma (NSCLC) is sometimes treated with surgery, while small cell lung carcinoma (SCLC) usually responds better to chemotherapy and radiation. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in nonsmokers, who account for as many as 15% of cases , is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.
Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage (degree of spread), and the patient's performance status. Possible treatments include surgery, chemotherapy, and radiotherapy. With treatment, the five-year survival rate is 14%.
For more information about Lung cancer, read the full article at
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News tagged with lung cancer
Scientists crack gene code of common cancers
Dec 17, 2009 |
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Two common forms of cancer have been genetically mapped for the first time, British scientists announced, in a major breakthrough in understanding the diseases.
Adverse consequences of obesity may be greater than previously thought
Dec 23, 2009 |
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The link between obesity and cardiovascular mortality may be substantially underestimated, while some of the adverse consequences of being underweight may be overstated, concludes a study published in the British Medical ...
Pistachios may reduce lung cancer risk
Dec 08, 2009 |
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A diet that incorporates a daily dose of pistachios may help reduce the risk of lung and other cancers, according to data presented at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference, ...
Lung cancer and melanoma laid bare: First comprehensive analysis of two cancer genomes
Dec 16, 2009 |
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Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes. All cancers are caused by mutations in the DNA of cancer cells which are acquired during a person's lifetime. ...
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Decline of hormone therapy decreases breast cancer cases, analysis finds
Dec 09, 2009 |
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The declining use of hormone therapy among women has led to 6,000 fewer invasive breast cancer cases a year, according to an analysis by researchers at the University of Wisconsin-Madison. The research quantifies and advances ...
Secondhand smoke exposure in childhood increases lung cancer risk later in life
Dec 03, 2009 |
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Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.
Experts: Colon cancer deaths could make big drop
Dec 07, 2009 |
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(AP) -- Colon cancer deaths could drop dramatically in the next decade because of better screening and treatment, according to an optimistic new prediction by top researchers.
Scientists use DNA sequencing to attack lung cancer
Dec 16, 2009 |
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Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with cigarette smoke bind to and chemically modify human DNA, ultimately ...
Gefitinib improves survival compared with standard chemotherapy in lung cancer patients with genetic mutation
Dec 20, 2009 |
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Patients with the most common form of lung cancer (non-small-cell lung cancer) who have mutations in the epidermal growth factor receptor (EGFR) gene have significantly improved progression-free survival if they are treated ...
Research yields new agent for some drug-resistant non-small cell lung cancers
Dec 23, 2009 |
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The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant ...
Scientists discover genetic pattern that indicates early-stage lung cancer
Dec 01, 2009 |
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Wistar Institute researchers and collaborators from the University of Pennsylvania and New York University have identified immune system markers in the blood which indicate early-stage lung tumors in people at high risk for ...
Study shows modest improvement in advanced lung cancer overall survival rates
Dec 01, 2009 |
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Research released in the December 2009 issue of the Journal of Thoracic Oncology sought to determine whether the survival improvement among patients with metastatic lung cancer has improved over the last two decades as rep ...
Racial disparity in lung cancer rates narrowed in young adults due to larger decrease in smoking
Dec 03, 2009 |
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Effective prevention of smoking among teenagers, particularly black teenagers, is narrowing the disparity in lung cancer rates between blacks and whites, according to a report published in Cancer Epidemiology, Biomarkers & ...
Repeat negative CT scan for lung cancer does not encourage ex-smokers to resume the habit
Dec 04, 2009 |
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Assurance of a cancer-free status did not prompt people participating in a long-term computerized tomography (CT) lung-cancer screening program to pick up their cigarettes again, researchers wrote in a study published in ...
