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Lung cancer
hideLung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women (after breast cancer), is responsible for 1.3 million deaths worldwide annually. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.
The main types of lung cancer are small cell lung carcinoma and non-small cell lung carcinoma. This distinction is important, because the treatment varies; non-small cell lung carcinoma (NSCLC) is sometimes treated with surgery, while small cell lung carcinoma (SCLC) usually responds better to chemotherapy and radiation. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in nonsmokers, who account for as many as 15% of cases , is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.
Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage (degree of spread), and the patient's performance status. Possible treatments include surgery, chemotherapy, and radiotherapy. With treatment, the five-year survival rate is 14%.
For more information about Lung cancer, read the full article at
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News tagged with lung cancer
Lung cancer and melanoma laid bare: First comprehensive analysis of two cancer genomes
Dec 16, 2009 |
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Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes. All cancers are caused by mutations in the DNA of cancer cells which are acquired during a person's lifetime. ...
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Researchers use drug-radiation combo to eradicate lung cancer
Oct 29, 2009 |
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Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Study links cigarette changes to rising lung risk
May 18, 2009 |
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(AP) -- It may be riskier on the lungs to smoke cigarettes today than it was a few decades ago - at least in the U.S., says new research that blames changes in cigarette design for fueling a certain type ...
Report: Most Americans in areas with unhealthy air
Apr 29, 2009 |
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(AP) -- Sixty percent of Americans live in areas with unhealthy air pollution levels, despite a growing green movement and more stringent laws aimed at improving air quality, the American Lung Association ...
When Genes Cooperate, Lung Cancer Grows and Spreads
Mar 09, 2009 |
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(PhysOrg.com) -- The combined expression of three specific genes in lung cancer tumors may predict both cancer growth and a poorer prognosis, according to a study led by researchers in the Duke Institute for Genome Sciences ...
Study links smoking with most male cancer deaths
Jan 21, 2009 |
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The association between tobacco smoke and cancer deaths — beyond lung cancer deaths — has been strengthened by a recent study from a UC Davis researcher, suggesting that increased tobacco control efforts could save more lives ...
Common food additive found to increase risk and speed spread of lung cancer
Dec 29, 2008 |
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New research in an animal model suggests that a diet high in inorganic phosphates, which are found in a variety of processed foods including meats, cheeses, beverages, and bakery products, might speed growth of lung cancer ...
Scientists find new genes linked to lung cancer
Oct 22, 2008 |
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Working as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common ...
Research yields new agent for some drug-resistant non-small cell lung cancers
11 hours ago |
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The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant ...
Adverse consequences of obesity may be greater than previously thought
20 hours ago |
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The link between obesity and cardiovascular mortality may be substantially underestimated, while some of the adverse consequences of being underweight may be overstated, concludes a study published in the British Medical ...
Scientists crack gene code of common cancers
Dec 17, 2009 |
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Two common forms of cancer have been genetically mapped for the first time, British scientists announced, in a major breakthrough in understanding the diseases.
Scientists use DNA sequencing to attack lung cancer
Dec 16, 2009 |
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Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with cigarette smoke bind to and chemically modify human DNA, ultimately ...
Decline of hormone therapy decreases breast cancer cases, analysis finds
Dec 09, 2009 |
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The declining use of hormone therapy among women has led to 6,000 fewer invasive breast cancer cases a year, according to an analysis by researchers at the University of Wisconsin-Madison. The research quantifies and advances ...
Pistachios may reduce lung cancer risk
Dec 08, 2009 |
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A diet that incorporates a daily dose of pistachios may help reduce the risk of lung and other cancers, according to data presented at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference, ...
