News tagged with marrow failure
Ontario's first cardiac stem cell transplant performed last week
Heart failure is a leading cause of death in Canada. As part of the ongoing IMPACT-CABG clinical trial to treat advanced heart failure, physicians at the Peter Munk Cardiac Centre performed the first cardiac stem cell transplant ...
Medicine & Health / Cardiology
Jan 26, 2012 |
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New findings about the way cells work could lead to a test and therapy for kidney failure caused by E. coli
Ever since the water supply in Walkerton, Ont., was contaminated by E. coli in 2000, Dr. Philip Marsden has been trying to figure out just how a toxin released by that particular strain of the bacteria causes kidney damage ...
Jan 10, 2012 |
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Towards more effective treatment for multiple myeloma
A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, ...
Jan 09, 2012 |
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Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient
Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease, ...
Dec 12, 2011 |
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Results triple researchers' projections with use of adult stem cells for heart failure
Patients suffering from heart failure due to a previous myocardial infarction showed an average of 12 percent improvement one year following an investigative treatment that involved infusing them with their ...
Nov 14, 2011 |
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Delayed stem cell therapy following heart attack is safe but not effective
NIH-funded trial shows that therapy with bone-marrow derived cells does not improve heart function after six months; future clinical benefits still possible.
Medicine & Health / Cardiology
Nov 14, 2011 |
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Researchers discover gene defect that predisposes people to leukemia
A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts ...
Sep 04, 2011 |
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Standard aplastic anemia therapy improves patient outcomes better than newer version
A comparison clinical study of two aplastic anemia treatments found that ATGAM, currently the only licensed aplastic anemia drug in the United States, improved blood cell counts and survival significantly more than did Thymoglobulin, ...
Aug 04, 2011 |
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New evidence of the benefits of home dialysis for kidney patients
Researchers at St. Michael's Hospital have found more evidence of the benefits of home dialysis for patients with kidney failure.
Jun 21, 2011 |
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Study of stem cell diseases advanced by new technique
A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem ...
May 23, 2011 |
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First U.S. patient enrolled in stem cell transplantation/cardiac bypass study aimed at improving heart failure
A 59-year-old Houston man became the first individual in the United States to enroll in a study using stem cell transplantation during cardiac bypass to treat severe heart failure.
Medicine & Health / Cardiology
May 12, 2011 |
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Key cause of bone marrow failure identified
(Medical Xpress) -- Researchers funded by Leukaemia & Lymphoma Research and the Medical Research Council (MRC) have identified one of the first steps that can cause bone marrow failure and eventually lead to blood cancers. ...
May 03, 2011 |
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Bone marrow cells may significantly reduce risk of second heart attack
Cells from heart attack survivors' own bone marrow reduced the risk of death or another heart attack when they were infused into the affected artery after successful stent placement, according to research reported in the ...
Dec 08, 2009 |
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Mice regain ability to extend telomeres suggesting potential for dyskeratosis congenita therapy
The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience ...
Oct 19, 2009 |
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Early heart attack therapy with bone marrow extract improves cardiac function
A UCSF study for the treatment of heart failure after heart attack found that the extract derived from bone marrow cells is as effective as therapy using bone marrow stem cells for improving cardiac function, decreasing the ...
Jun 29, 2009 |
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