News tagged with marrow toxicity
Proton therapy and concurrent chemotherapy may reduce bone marrow toxicity in advanced lung cancer
Nov 13, 2008 |
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Patients treated for locally advanced non-small cell lung cancer who receive chemotherapy and proton beam therapy have fewer instances of bone marrow toxicity than patients who receive the standard treatment of intensity-modulated ...
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Scientists make multiple types of white blood cells directly from embryonic and adult stem cells
Aug 10, 2009 |
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(PhysOrg.com) -- In an advance that could help transform embryonic stem cells into a multipurpose medical tool, scientists at the University of Wisconsin-Madison have transformed these versatile cells into ...
Death-inducing proteins key to complications of bone marrow transplantation
4 hours ago |
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Treatment for a number of cancers and other medical conditions is transplantation with bone marrow from a genetically nonidentical individual (a process known as allogeneic bone marrow transplantation [allo-BMT]).
Study finds it's safe to treat HER2-positive breast cancer with trastuzumab and adjuvant radiation
Nov 03, 2009 |
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Standard adjuvant treatment for HER2-positive breast cancer patients, following primary surgery for their cancer, is Trastuzumab (Herceptin)--typically used in combination with chemotherapy. However, a new study by researchers ...
Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
Feb 26, 2008 |
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A review of previously published research suggests that stem cells harvested from an adult’s blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according ...
A balancing act in Parkinson's disease: Phosphorylation of alpha-synuclein
Oct 12, 2009 |
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Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. Previous studies have indicated that phosphorylation of alpha-synuclein at amino acid 129 (Ser129) is a key event ...
Stem cells offer new hope for kidney disease patients
Oct 15, 2009 |
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Several cell-based therapy approaches could provide new treatments for patients with Alport syndrome, reports an upcoming paper in the Journal of the American Society of Nephrology (JASN). "Our study opens ...
Stripping leukemia-initiating cells of their 'invisibility cloak'
Jul 23, 2009 |
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Two new studies reveal a way to increase the body's appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting ...
Discovery of enzyme structure points way to creating less toxic anti-HIV drugs
Oct 15, 2009 |
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By discovering the atomic structure of a key human enzyme, researchers at The University of Texas at Austin have pointed the way toward designing anti-HIV drugs with far less toxic side effects.
Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
Sep 01, 2009 |
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Directly inhibiting the activity of a key protein mediator of inflammation reduced radiation toxicity in zebrafish embryos, and may ultimately be of help to patients receiving radiation therapy, according to researchers from ...
Researchers Discover Mutations in Two Genes that Cause Early-Onset Inflammatory Bowel Disease
Nov 05, 2009 |
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(PhysOrg.com) -- An international team including researchers with the National Institutes of Health has discovered that mutations in either of two related genes cause a severe and rare form of inflammatory bowel disease (IBD) ...
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