DNA structure
hideDNA structure shows a variety of forms, both double-stranded and single-stranded. The mechanical properties of DNA, which are directly related to its structure, are a significant problem for cells. Every process which binds or reads DNA is able to use or modify the mechanical properties of DNA for purposes of recognition, packaging and modification. The extreme length (a chromosome may contain a 10 cm long DNA strand), relative rigidity and helical structure of DNA has led to the evolution of histones and of enzymes such as topoisomerases and helicases to manage a cell's DNA. The properties of DNA are closely related to its molecular structure and sequence, particularly the weakness of the hydrogen bonds and electronic interactions that hold strands of DNA together compared to the strength of the bonds within each strand.
Experimental techniques which can directly measure the mechanical properties of DNA are relatively new, and high-resolution visualization in solution is often difficult. Nevertheless, scientists have uncovered large amount of data on the mechanical properties of this polymer, and the implications of DNA's mechanical properties on cellular processes is a topic of active current research.
It is important to note the DNA found in many cells can be macroscopic in length - a few centimetres long for each human chromosome. Consequently, cells must compact or "package" DNA to carry it within them. In eukaryotes this is carried by spool-like proteins known as histones, around which DNA winds. It is the further compaction of this DNA-protein complex which produces the well known mitotic eukaryotic chromosomes.
For more information about DNA structure, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with mechanical properties
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Nov 27, 2009 |
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Prized for their impressive antlers, red deer have been caught in the hunters' sights for generations. But a deer's antlers are much more than decorative. They are lethal weapons that stags crash together when duelling. John ...
Understanding mechanical properties of silicon nanowires paves way for nanodevices
Nanotechnology / Nanomaterials
Nov 11, 2009 |
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Silicon nanowires are attracting significant attention from the electronics industry due to the drive for ever-smaller electronic devices, from cell phones to computers. The operation of these future devices, ...
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Super cool atom thermometer
12 hours ago |
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As physicists strive to cool atoms down to ever more frigid temperatures, they face the daunting task of developing new, reliable ways of measuring these extreme lows. Now a team of physicists has devised ...
Physicist Jack Harris Is Honored by DARPA as One of Nation's 'Rising Stars'
Dec 04, 2009 |
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(PhysOrg.com) -- Jack Harris, an associate professor of physics, has received one of this year's Young Faculty Awards (YFA) from the Defense Advanced Research Projects Agency (DARPA). He is one of 33 "rising stars" across ...
Shape shifters: Researchers create new breed of antennas
Dec 01, 2009 |
4.7 / 5 (13) |
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Antennas aren't just for listening to the radio anymore. They're used in everything from cell phones to GPS devices. Research from North Carolina State University is revolutionizing the field of antenna design ...
Elastography reduces unnecessary breast biopsies
Nov 30, 2009 |
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Elastography is an effective, convenient technique that, when added to breast ultrasound, helps distinguish cancerous breast lesions from benign results, according to an ongoing study presented today at the annual meeting ...
Tissue tension regulates tumor progression
Nov 23, 2009 |
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(PhysOrg.com) -- UCSF scientists have shown for the first time that the rigidity of a tissue can induce cancer. The research team identified an enzyme that is crucial for regulating tissue stiffness and demonstrated that ...
Water droplets direct self-assembly process in thin-film materials
Nanotechnology / Nanomaterials
Nov 23, 2009 |
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You can think of it as origami - very high-tech origami. Researchers at the University of Illinois have developed a technique for fabricating three-dimensional, single-crystalline silicon structures from thin films by coupling ...
Measuring and modeling blood flow in malaria
Nov 23, 2009 |
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When people have malaria, they are infected with Plasmodium parasites, which enter the body from the saliva of a mosquito, infect cells in the liver, and then spread to red blood cells. Inside the blood cells, the parasites ...
NJIT receives funding to improve Big Bear Telescope, study solar energy
Nov 20, 2009 |
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NJIT researchers are at work on many scientific and technological frontiers. The National Science Foundation has recently provided support that totals nearly $4.3 million for the diverse efforts of the following ...
Atomic-level Snapshot Catches Protein Motor in Action (w/ Video)
Nov 20, 2009 |
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(PhysOrg.com) -- The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory using a state-of-the-art protein ...
Active hearing process in mosquitoes
Nov 20, 2009 |
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A mathematical model has explained some of the remarkable features of mosquito hearing. In particular, the male can hear the faintest beats of the female's wings and yet is not deafened by loud noises.
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