Nanodiamonds are 2–8 nm carbon nanoparticles, which can be easily functionalized with various chemical groups like carboxylic groups or drugs. Previous research has shown that actively dividing cells are more likely to ...
Bio & Medicine
Nov 29, 2023
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60
Melanomas are the most common oral cancers in dogs. They are highly metastatic and conventional chemotherapy does not increase survival time. Canine oral melanomas are similar to human melanomas; thus, research is being conducted ...
Veterinary medicine
Jun 23, 2023
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3
None of us are born with a fully functioning immune system, and the first few months of life are crucial for establishing strong lifelong defenses. Better understanding how germs influence the development of human immunology ...
Cell & Microbiology
Jun 13, 2023
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80
A research team led by Professor Byung-Chang Suh has investigated the real-time effect of the G-protein cycle, which acts as a switch in the body, on the structural changes in G protein-coupled receptors (GPCRs). Their study ...
Molecular & Computational biology
Mar 31, 2023
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141
Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern ...
Cell & Microbiology
Mar 6, 2023
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11
Research led by Queen Mary University of London, King's College London and the Francis Crick Institute has identified a protein that makes melanoma, the most serious type of skin cancer, more aggressive by giving cancer cells ...
Cell & Microbiology
Jan 9, 2023
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49
Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, ...
Cell & Microbiology
Sep 1, 2022
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59
Better treatments for some of cancer's deadliest forms could be closer due to a University of California, Irvine-led discovery about how a certain protein is activated in tumor cells. The finding, spearheaded by researchers ...
Cell & Microbiology
Jul 18, 2022
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73
There are few places farther from your medicine cabinet than the tissues of an ascidian, or "sea squirt," on the icy Antarctic sea floor—but this is precisely where scientists are looking to find a new treatment for melanoma, ...
Plants & Animals
Dec 1, 2021
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617
Studies conducted in yeast show that exposure to ultraviolet light (UV) induces new types of DNA damage that may cause the deadliest form of skin cancer, malignant melanoma.
Molecular & Computational biology
Nov 17, 2020
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40
Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
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