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Memantine

Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Despite years of research, whether memantine has any effect in mild to moderate Alzheimer's disease is unknown.

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Memantine drug ineffective against Alzheimer's in Down's syndrome patients

(Medical Xpress) -- Memantine, a drug used to treat patients with Alzheimer’s disease, is ineffective for people with Down’s syndrome aged 40 and over, according to a study led by researchers at ...

Medicine & Health / Medications

created Jan 11, 2012 | popularity not rated yet | comments 0

Long struggle for appropriately processed manufacturer data leads to a new assessment of memantine

After the manufacturer of the Alzheimer's drug memantine submitted a supplementary analysis of study data, the German Institute for Quality and Efficiency in Health Care (IQWiG) sees proof of a benefit of the drug for cognitive ...

Medicine & Health / Diseases

created Apr 27, 2011 | popularity not rated yet | comments 0

Research contributes to revised decision on availability of Alzheimer's drugs

A review of research evidence produced by researchers from the Peninsula Technology Assessment Group, part of the Peninsula College of Medicine and Dentistry, has played a pivotal role in the decision by the National Institute ...

Medicine & Health / Diseases

created Jan 18, 2011 | popularity not rated yet | comments 0

Pathological gambling may be successfully treated with medications for substance addiction

Pathological gambling can be successfully treated with medications that decrease urges and increase inhibitions, according to researchers at the annual meeting of the American College of Neuropsychopharmacology (ACNP). Researchers ...

Medicine & Health / Psychology & Psychiatry

created Dec 10, 2009 | popularity 5 / 5 (1) | comments 0

Researchers solve structure of NMDA receptor unit that could be drug target for neurological diseases

A team of scientists at Cold Spring Harbor Laboratory reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's, Parkinson's, and other serious ...

Chemistry / Biochemistry

created Nov 12, 2009 | popularity not rated yet | comments 0

Benefit of memantine in the treatment of Alzheimer's disease not proven

There is no scientific proof that patients with moderate or severe Alzheimer's disease benefit from drugs containing the agent memantine. This is the conclusion in the final report that the Institute for Quality and Efficiency ...

Medicine & Health / Medications

created Oct 28, 2009 | popularity 5 / 5 (1) | comments 0

Migraine prevention by targeting glutamate receptors?

When migraine strikes, because of severe pain, often accompanied by nausea and sensitivity to light and sound, sufferers are effectively disabled for up to 72 hours. Since they are forced to stop what they are doing until ...

Medicine & Health / Research

created Apr 29, 2009 | popularity not rated yet | comments 0