An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
Molecular & Computational biology
Apr 23, 2024
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42
Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s. In a new study, molecular biologist Steven Van Doren, ...
Molecular & Computational biology
Aug 31, 2023
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42
In drug delivery, the therapeutic behavior of the nanocarriers is limited by the "foreign" character of their surface. Despite the wide range of sophisticated coatings available, immune cells often identify these synthetic ...
Bio & Medicine
Jul 13, 2023
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31
Codonopsis lanceolata, more commonly referred to as "deodeok," is used as a medicinal herb in South Korea. It is cultivated in large quantities and has been an integral part of Korean cuisine across history. Aster koraiensis, ...
Biochemistry
Nov 11, 2022
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71
An interdisciplinary team of researchers at the Indian Institute of Science (IISc) has used robust computer simulations to understand how HIV, the virus that causes AIDS, fuses with the host cell membrane. Published in the ...
Molecular & Computational biology
Feb 8, 2021
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7
Many viruses, including that perennial winter affliction, the influenza virus, are protected by a lipid membrane on loan from the host cell. The fusion proteins on the surface of the membrane are tasked with merging the lipid ...
Cell & Microbiology
Apr 5, 2019
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5
New 3-D maps of water distribution during cellular membrane fusion are accelerating scientific understanding of cell development, which could lead to new treatments for diseases associated with cell fusion. Using neutron ...
General Physics
Sep 21, 2018
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281
Googling "SNARE proteins," neuroscientist Edward Chapman gets a screenful of images showing corkscrew-shaped molecules, intertwined as they seize the outer membranes of two cells. "They did not give us credit at Wikipedia, ...
Cell & Microbiology
Jan 31, 2018
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190
The protein that helps the sperm and egg fuse together in sexual reproduction can also fuse regular cells together. Recent findings by a team of biomedical researchers from the Technion-Israel Institute of Technology, Argentina, ...
Cell & Microbiology
Feb 14, 2017
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31
Every time a hormone is released from a cell, every time a neurotransmitter leaps across a synapse to relay a message from one neuron to another, the cell must undergo exocytosis. This is the process responsible for transporting ...
Cell & Microbiology
Jan 23, 2017
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