Related topics: proceedings of the national academy of sciences , cells , genes , protein , gene expression
Messenger RNA
hideMessenger ribonucleic acid (mRNA) is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein. In mRNA as in DNA, genetic information is encoded in the sequence of nucleotides arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons that terminate protein synthesis. This process requires two other types of RNA: transfer RNA (tRNA) mediates recognition of the codon and provides the corresponding amino acid, while ribosomal RNA (rRNA) is the central component of the ribosome's protein manufacturing machinery.
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News tagged with messenger rna
Argonautes: A big turn-off for proteins
Feb 01, 2010 |
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Johns Hopkins scientists believe they may have figured out how genetic snippets called microRNAs are able to shut down the production of some proteins.
EGFR gene signature predicts non-small cell lung cancer prognosis
Jan 13, 2010 |
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Epidermal growth factor receptor (EGFR) is a validated therapeutic target for non-small cell lung cancer. Researchers have now discovered a 93-gene signature that is associated with the presence of EGFR mutations in tumors ...
In early heart development, genes work in tandem
Jan 12, 2010 |
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Studying genes that regulate early heart development in animals, scientists have solved a puzzle about one gene's role, finding that it acts in concert with a related gene. Their finding contributes to understanding how the ...
Researchers Identify microRNA targets in C. elegans
Jan 10, 2010 |
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MicroRNAs (miRNAs) are non-coding RNAs that impact almost every aspect of biology. In recent years, they have been strongly implicated in stem cell biology, tissue and organism development, as well as human conditions ranging ...
New and improved RNA interference
Jan 04, 2010 |
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(PhysOrg.com) -- Researchers use RNA interference to silence multiple genes at once. The advance, which one expert calls a 'substantial breakthrough,' could lead to new treatments for liver diseases.
New RNA interference technique can silence up to five genes
Dec 28, 2009 |
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Researchers at MIT and Alnylam Pharmaceuticals report this week that they have successfully used RNA interference to turn off multiple genes in the livers of mice, an advance that could lead to new treatments ...
Transcription factors guide differences in human and chimp brain function
Dec 07, 2009 |
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Humans share at least 97 percent of their genes with chimpanzees, but, as a new study of transcription factors makes clear, what you have in your genome may be less important than how you use it.
Cells defend themselves from viruses, bacteria with armor of protein errors
Nov 25, 2009 |
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When cells are confronted with an invading virus or bacteria or exposed to an irritating chemical, they protect themselves by going off their DNA recipe and inserting the wrong amino acid into new proteins to defend them ...
Atomic-level Snapshot Catches Protein Motor in Action (w/ Video)
Nov 20, 2009 |
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(PhysOrg.com) -- The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory using a state-of-the-art protein ...
'Cross-talk' mechanism contributes to colorectal cancer
Nov 13, 2009 |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
Explained: RNA interference
Nov 12, 2009 |
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Every high school biology student learns the basics of how genes are expressed: DNA, the cell’s master information keeper, is copied into messenger RNA, which carries protein-building instructions to the ribosome, ...
Two-pronged protein attack could be source of SARS virulence
Oct 29, 2009 |
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Ever since the previously unknown SARS virus emerged from southern China in 2003, University of Texas Medical Branch at Galveston virologists have focused on finding the source of the pathogen's virulence — its ability to ...
New research shows how mobile DNA survives -- and thrives -- in plants, animals
Oct 21, 2009 |
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(PhysOrg.com) -- Bits of movable DNA called transposable elements or TEs fill up the genomes of plants and animals, but it has remained unclear how a genome can survive a rapid burst of hundreds, even thousands of new TE ...
Silence of the genes
Oct 13, 2009 |
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The molecular architecture of a protein complex that helps determine the fate of human cells has been imaged for the first time by researchers with the U.S. Department of Energy's Lawrence Berkeley National ...
Lung cancer suppresses miR-200 to invade and spread
Sep 14, 2009 |
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Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson Cancer Center report ...
