News tagged with metastasis
Metastatic breast cancer hitches a free ride from the immune system
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed ...
Feb 10, 2012 |
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How early breast tumors become deadly: A small group of molecules might hold the answer
Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness ...
Feb 07, 2012 |
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Cancer patients' pain can be helped by psychosocial interventions, say researchers
Researchers at Moffitt Cancer Center, who teamed with colleagues at five universities around the United States, analyzed past studies of cancer-related pain reduction and found that psychosocial interventions can have a beneficial ...
Jan 30, 2012 |
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Cutting off the oxygen supply to serious diseases
A new family of proteins which regulate the human body's 'hypoxic response' to low levels of oxygen has been discovered by scientists at Barts Cancer Institute at Queen Mary, University of London and The University of Nottingham.
Jan 30, 2012 |
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New method to manage stress responses for more successful tumor removal
The week before and two weeks after surgery are a critical period for the long-term survival rate of cancer patients. Physiological and psychological stresses caused by the surgery itself can inhibit the body's immune responses, ...
Jan 30, 2012 |
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Scientists illuminate cancer cells' survival strategy
A team led by scientists at The Scripps Research Institute has discovered key elements of a strategy commonly used by tumor cells to survive when they spread to distant organs. The finding could lead to drugs that could inhibit ...
Jan 26, 2012 |
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Study finds that tumor cells can prevent cancer spread
A new study finds that a group of little-explored cells in the tumor microenvironment likely serve as important gatekeepers against cancer progression and metastasis. Published in the January 17 issue of Cancer Cell, these ...
Jan 17, 2012 |
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Agent shows ability to suppress brain metastasis and related damage
(Medical Xpress) -- Scientists are one step closer to repairing the damage caused by brain metastasis, a major challenge in cancer treatment, according to data published in Cancer Research, a journal of the American Associ ...
Jan 03, 2012 |
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New synthetic molecules treat autoimmune disease in mice
A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...
Dec 25, 2011 |
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UK researchers present findings from Kentucky breast cancer patients with disease relapse
The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this ...
Dec 23, 2011 |
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In cancer, molecular signals that recruit blood vessels also trigger metastasis
(Medical Xpress) -- Cancer cells are most deadly when theyre on the move able not only to destroy whatever organ they are first formed in, but also to create colonies elsewhere in the body. New ...
Dec 19, 2011 |
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Researchers describe a new genetic program that converts static cells into mobile invasive cells
Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells -which group together and are static- losing adhesion and moving ...
Dec 15, 2011 |
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Researchers discover new way to form extracellular vesicles
Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals ...
Nov 17, 2011 |
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Denosumab delays development of prostate cancer bone metastasis
An international clinical trial has found that treatment with a drug that suppresses the normal breakdown of bone can delay the development of bone metastases in men with prostate cancer. The study, receiving Online First ...
Nov 16, 2011 |
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Uncovering a key player in metastasis
About 90 percent of cancer deaths are caused by secondary tumors, known as metastases, which spread from the original tumor site.
Nov 15, 2011 |
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Metastasis
Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.
Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).
When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.
For more information about Metastasis, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.