Metastasis
hideMetastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.
Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).
When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.
For more information about Metastasis, read the full article at
Wikipedia.
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News tagged with metastasis
Tissue tension regulates tumor progression
Nov 23, 2009 |
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(PhysOrg.com) -- UCSF scientists have shown for the first time that the rigidity of a tissue can induce cancer. The research team identified an enzyme that is crucial for regulating tissue stiffness and demonstrated that ...
Researchers create 'fly paper' to capture circulating cancer cells
Nov 18, 2009 |
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Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor.
Experimental agent reduces breast cancer metastasis to bone
Nov 03, 2009 |
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Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer. In a study in mice, the team of researchers ...
MicroRNA-mediated metastasis suppression
Oct 28, 2009 |
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Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis.
A case of post-gastrectomy acute pancreatitis
Oct 16, 2009 |
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A clinical research team from Taiwan reported a case of asymptomatic pancreatic divisum who underwent palliative subtotal gastrectomy for an advanced gastric cancer with liver metastasis. They concluded for patients with ...
Scientists find way to predict stomach cancer relapses
Oct 05, 2009 |
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Researchers at the National Cancer Center in Japan have developed a system for detecting 70 percent of postoperative stomach cancer relapses, according to sources.
Researchers identify gene that regulates breast cancer metastasis
Oct 05, 2009 |
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Researchers at The Wistar Institute have identified a key gene (KLF17) involved in the spread of breast cancer throughout the body. They also demonstrated that expression of KLF17 together with another gene (Id1) known to ...
Researchers determine the composition of centromeric chromatin
Sep 28, 2009 |
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The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical ...
Ultrasound can predict tumor burden and survival in melanoma patients
Sep 23, 2009 |
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Berlin, Germany: Researchers have shown for the first time that patterns of ultrasound signals can be used to identify whether or not cancer has started to spread in melanoma patients, and to what extent. The discovery enables ...
Scientists identify gene that predicts post-surgical survival from brain metastasis of breast cancer patients
Sep 01, 2009 |
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Researchers at the National Cancer Institute have identified a gene that may play a role in breast cancer metastasis to the brain, according to a report in Molecular Cancer Research, a journal of the Americ ...
Breakthrough uses light to manipulate cell movement
Aug 19, 2009 |
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One of the biggest challenges in scientists' quest to develop new and better treatments for cancer is gaining a better understanding of how and why cancer spreads. Recent breakthroughs have uncovered how ...
Advances in lung cancer research announced at conference
Aug 07, 2009 |
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Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference.
'Microfluidic Palette' May Paint Clearer Picture of Biological Processes
Jul 28, 2009 |
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(PhysOrg.com) -- The masterpieces that spring from the talents of Rembrandt, Van Gogh and other artists often begin with the creation of a gradient of colors on a palette. In a similar manner, researchers ...
Protein that promotes cancer cell growth identified
Jul 24, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer ...
Preventing Prostate Cancer to Bone Metastasis
Jul 13, 2009 |
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(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...
