Related topics: breast cancer



Metastasis

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Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.

Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.

For more information about Metastasis, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with metastasis

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'Live' imaging reveals breast cancer cells' transition to metastasis

Medicine & Health / Cancer

created Dec 06, 2009 | popularity not rated yet | comments 0

The spread, or metastasis, of individual breast cancer cells from the main tumor into the blood circulation to the lungs and other body tissues and organs is under the control of a growth factor abbreviated TGFb, according ...


Tissue tension regulates tumor progression

Medicine & Health / Cancer

created Nov 23, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- UCSF scientists have shown for the first time that the rigidity of a tissue can induce cancer. The research team identified an enzyme that is crucial for regulating tissue stiffness and demonstrated that ...


Researchers create 'fly paper' to capture circulating cancer cells

Researchers create 'fly paper' to capture circulating cancer cells

Chemistry / Biochemistry

created Nov 18, 2009 | popularity 4 / 5 (5) | comments 1

Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor.


Breakthrough uses light to manipulate cell movement

Breakthrough uses light to manipulate cell movement

Chemistry / Biochemistry

created Aug 19, 2009 | popularity 5 / 5 (6) | comments 1

One of the biggest challenges in scientists' quest to develop new and better treatments for cancer is gaining a better understanding of how and why cancer spreads. Recent breakthroughs have uncovered how ...


Preventing Prostate Cancer to Bone Metastasis

Medicine & Health / Cancer

created Jul 13, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...


Researchers identify gene that regulates breast cancer metastasis

Medicine & Health / Cancer

created Oct 05, 2009 | popularity 5 / 5 (1) | comments 0

Researchers at The Wistar Institute have identified a key gene (KLF17) involved in the spread of breast cancer throughout the body. They also demonstrated that expression of KLF17 together with another gene (Id1) known to ...


Scientists identify gene that predicts post-surgical survival from brain metastasis of breast cancer patients

Scientists identify gene that predicts post-surgical survival from brain metastasis of breast cancer patients

Medicine & Health / Cancer

created Sep 01, 2009 | popularity 5 / 5 (3) | comments 0

Researchers at the National Cancer Institute have identified a gene that may play a role in breast cancer metastasis to the brain, according to a report in Molecular Cancer Research, a journal of the Americ ...


'Microfluidic Palette' May Paint Clearer Picture of Biological Processes

'Microfluidic Palette' May Paint Clearer Picture of Biological Processes

Chemistry / Biochemistry

created Jul 28, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- The masterpieces that spring from the talents of Rembrandt, Van Gogh and other artists often begin with the creation of a gradient of colors on a palette. In a similar manner, researchers ...


Exciting discovery could 'stop cancer from killing people'

Medicine & Health / Cancer

created Dec 15, 2008 | popularity 4.8 / 5 (65) | comments 11

Metastasis is the ability of cancer cells to spread from a primary site, to form tumours at distant sites. It is a complex process in which cell motility and invasion play a fundamental role. Essential to our understanding ...


RNA snippet suppresses spread of aggressive breast cancer

RNA snippet suppresses spread of aggressive breast cancer

Medicine & Health / Cancer

created Jun 13, 2009 | popularity 5 / 5 (1) | comments 1

High levels of a tiny fragment of RNA appear to suppress the spread of breast cancer in mice, according to researchers at Whitehead Institute for Biomedical Research.


Researchers discover, manipulate molecular interplay that moves cancer cells

Biology / Cell & Microbiology

created Mar 29, 2009 | popularity 5 / 5 (2) | comments 0

Based on research that reveals new insight into mechanisms that allow invasive tumor cells to move, researchers at the Mayo Clinic campus in Florida have a new understanding about how to stop cancer from spreading. A cancer ...


Researchers describe function of key protein in cancer spread

Chemistry / Biochemistry

created May 21, 2009 | popularity 4.5 / 5 (2) | comments 0

Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread ...


New technique may help detect potential breast cancer spread

Medicine & Health / Cancer

created May 08, 2009 | popularity 5 / 5 (2) | comments 0

A new phase III clinical trial of early stage breast cancer patients has shown that a molecule designed to home in on nearby lymph nodes is just as accurate as current techniques, but faster, more specific and easier to use.


Scientists identify molecular powerbrokers involved in cancer's spread

Medicine & Health / Cancer

created Jun 01, 2009 | popularity 5 / 5 (1) | comments 1

You know the guy -- he's your Facebook friend. The one who knows everyone. Secure at the center of a dense web of relationships, he suggests causes and reconnects old friends like a skilled matchmaker. Scientists have known ...


New discovery raises doubts about current bladder treatment

Medicine & Health / Cancer

created Mar 25, 2009 | popularity 3.5 / 5 (2) | comments 0

Researchers at the University of Virginia Health System have found that one of the genes commonly thought to promote the growth and spread of some types of cancers is in fact beneficial in bladder cancer - a major discovery ...