News tagged with metformin
Solving the mystery of an old diabetes drug that may reduce cancer risk
In 2005, news first broke that researchers in Scotland found unexpectedly low rates of cancer among diabetics taking metformin, a drug commonly prescribed to patients with Type II diabetes. Many follow-up studies reported ...
Jan 18, 2012 |
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Added benefit of linagliptin is not proven
Linagliptin (trade name: Trajenta) has been approved since August 2011 to improve blood glucose control ("glycaemic control") in adults with type 2 diabetes mellitus whose elevated blood glucose levels are inadequately controlled ...
Medicine & Health / Medications
Jan 06, 2012 |
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Researchers test a drug-exercise program designed to prevent type 2 diabetes
(Medical Xpress) -- Kinesiology researcher Barry Braun of the University of Massachusetts Amherst and colleagues recently reported unexpected results of a study suggesting that exercise and one of the most commonly prescribed ...
Dec 06, 2011 |
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Diabetes drug metformin shows promise in reducing risk of cancer
An inexpensive drug that treats Type-2 diabetes has been shown to prevent a number of natural and man-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State ...
Nov 23, 2011 |
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Scientists use diabetes drug in double hit to starve cancer cells
(Medical Xpress) -- UK scientists have discovered how blocking a key controller of energy production in cancer cells and treating them with a diabetes drug, metformin, effectively starves cancer cells. The research1 is published ...
Aug 29, 2011 |
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Metformin and exercise combination less effective for glucose control
University of Alberta researchers looking at the effects of metformin and exercise in Type 2 diabetes patients found that a combination of these modalities didn't lower glucose control as much as hoped. Surprisingly, study ...
Aug 19, 2011 |
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Does menopause matter when it comes to diabetes?
Menopause has little to no impact on whether women become more susceptible to diabetes, according to a one-of-a-kind study.
Jul 26, 2011 |
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Vitamin E or metformin may not be effective for treating liver disease in children and teens
In contrast to previous preliminary data, use of vitamin E or the diabetes drug metformin was not superior to placebo on a measured outcome for treating nonalcoholic fatty liver disease in children and adolescents, according ...
Apr 26, 2011 |
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Some diabetes drugs are better than others, according to new study
New research suggests that several commonly prescribed drugs for type 2 diabetes may not be as effective at preventing death and cardiovascular diseases, such as heart attacks and stroke, as the oral anti-diabetic drug, metformin.
Medicine & Health / Medications
Apr 07, 2011 |
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Diabetes treatment may also provide protection against endometrial cancer
Research led by Warwick Medical School at the University of Warwick has found that Metformin, a drug treatment used to treat diabetes and also in women with Polycystic vary syndrome (PCOS), may potentially ...
Apr 05, 2011 |
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Diabetes drug could work against Alzheimer's
Scientists from Berlin, Bonn and Dundee show in animal models that the diabetes drug metformin has an effect against one of the main causes of the Alzheimer's disease.
Nov 24, 2010 |
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Metformin may protect against lung cancer
Metformin, a drug commonly used to treat type 2 diabetes, shows potential in the prevention of tobacco-induced lung tumors, according to early research conducted at the National Cancer Institute (NCI).
Sep 01, 2010 |
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New use for old drugs in treating hepatitis C
Common drugs used to treat conditions such as diabetes and obesity could be used to successfully treat hepatitis C virus infection.
Jun 07, 2010 |
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Popular diabetes drug works differently than thought
The popular diabetes medication metformin works in different fashion than the current widely accepted view. This new finding could lead to wider use of the drug—particularly in people with cancer and diseases linked to TSC ...
May 04, 2010 |
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Metformin may prevent lung cancer in smokers
Metformin, a mainstay of treatment for patients with type 2 diabetes, may soon play a role in lung cancer prevention if early laboratory research presented here at the AACR 101st Annual Meeting 2010 is confirmed in clinical ...
Apr 19, 2010 |
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Metformin
Metformin (INN, pronounced /mɛtˈfɔrmɨn/, met-fawr-min; originally sold as Glucophage) is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function. Evidence is also mounting for its efficacy in gestational diabetes, although safety concerns still preclude its widespread use in this setting. It is also used in the treatment of polycystic ovary syndrome, and has been investigated for other diseases where insulin resistance may be an important factor.
When prescribed appropriately, metformin causes few adverse effects—the most common is gastrointestinal upset—and is associated with a low risk of hypoglycemia. Lactic acidosis (a buildup of lactate in the blood) can be a serious concern in overdose and when it is prescribed to people with contraindications, but otherwise, there is no significant risk. Metformin helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and is the only antidiabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes. As of 2010[update], metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines (the other being glibenclamide).
First synthesized and found to reduce blood sugar in the 1920s, metformin was forgotten for the next two decades as research shifted to insulin and other antidiabetic drugs. Interest in metformin was rekindled in the late 1940s after several reports that it could reduce blood sugar levels in people, and in 1957, French physician Jean Sterne published the first clinical trial of metformin as a treatment for diabetes. It was introduced to the United Kingdom in 1958, Canada in 1972, and the United States in 1995. Metformin is now believed to be the most widely prescribed antidiabetic drug in the world; in the United States alone, more than 48 million prescriptions were filled in 2010 for its generic formulations.
For more information about Metformin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
