News tagged with methyl groups
'Smothered' genes combine with mutations to yield poor outcome in cancer patients
Jul 15, 2008 |
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Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for ...
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Scientists take a step towards uncovering the histone code
Dec 20, 2009 |
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Researchers at Emory University School of Medicine have determined the structures of two enzymes that customize histones, the spool-like proteins around which DNA coils inside the cell.
A miR boost enables acute leukemia cells to mature
Apr 03, 2009 |
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A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, ...
Silenced genes as a warning sign of blood cancer
Aug 04, 2009 |
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In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence ...
Epigenetic research uncovers new targets for modification enzymes
Biology /
Apr 27, 2008 |
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Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows. The expanding field of epigenetics focuses on the multiple influences on DNA and surrounding molecules that determine ...
Paired microbes eliminate methane using sulfur pathway
Biology /
Jan 17, 2008 |
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Anaerobic microbes in the Earth's oceans consume 90 percent of the methane produced by methane hydrates – methane trapped in ice – preventing large amounts of methane from reaching the atmosphere. Researchers now have evidence ...
Scientists show how hematopoietic stem cell development is regulated
Oct 06, 2009 |
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During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation. These were the findings ...
Rodent studies suggest mother's diet can affect genes and offspring's risk of allergic asthma
Sep 18, 2008 |
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A pregnant mouse's diet can induce epigenetic changes that increase the risk her offspring will develop allergic asthma, according to researchers at National Jewish Health and Duke University Medical Center. Pregnant mice ...
Anti-cancer flower power
Aug 25, 2008 |
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Could a substance from the jasmine flower hold the key to an effective new therapy to treat cancer? Prof. Eliezer Flescher of The Sackler Faculty of Medicine, Tel Aviv University thinks so. He and his colleagues have developed ...
Researchers discover a new pathway that regulates inflammation
Mar 11, 2009 |
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Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens. But inflammation gone awry can also undermine health, ...
Changing smell of plants announces fungus attack
Oct 20, 2009 |
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(PhysOrg.com) -- Tomato plants under attack from the Botrytis fungus give off an aromatic substance that can be measured in greenhouses. This is the result of research performed by Roel Jansen with which he ...
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