News tagged with microrna
Anti-sense might make sense for treating liver cancer
A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The findings might offer a new therapy for this malignancy, which kills an estimated 549,000 people ...
Jan 03, 2012 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Jan 02, 2012 |
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No brakes on breast cancer cells
Scientists of the German Cancer Research Center have discovered a tiny RNA molecule, called miR-520, which at once blocks two important pathways in the development of cancer in cells. In estrogen receptor-negative ...
Dec 16, 2011 |
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Novel therapeutic target identified to decrease triglycerides and increase 'good' cholesterol
Researchers at NYU Langone Medical Center today announce findings published in the October 20 issue of Nature that show for the first time the inhibition of both microRNA-33a and microRNA-33b (miR-33a/b) with chemically modifi ...
Oct 20, 2011 |
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Small molecules can starve cancer cells
All cells in our body have a system that can handle cellular waste and release building blocks for recycling. The underlying mechanism is called autophagy and literally means "self-eating". Many cancer cells have increased ...
Oct 09, 2011 |
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Study links 23 microRNAs to laryngeal cancer
A Henry Ford Hospital study has identified 23 microRNAs for laryngeal cancer, a discovery that could yield new insight into what causes certain cells to grow and become cancerous tumors in the voice box.
Sep 13, 2011 |
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Ultrasensitive particles offer new way to find cancer
About 10 years ago, scientists discovered a new type of genetic material called microRNA, which appears to turn genes on or off inside a cell. More recently, they found that these genetic snippets often go ...
Aug 31, 2011 |
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Small molecules shed light on cancer therapies
Patients suffering from an aggressive brain cancer will benefit from the results of a University of Illinois study that could advance the development of targeted gene therapies and improve prognosis.
Aug 22, 2011 |
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Efficient process using microRNA converts human skin cells into neurons
The addition of two particular gene snippets to a skin cell's usual genetic material is enough to turn that cell into a fully functional neuron, report researchers from the Stanford University School of Medicine. The finding, ...
Jul 13, 2011 |
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MicroRNAs in the songbird brain respond to new songs (w/ video)
Whenever it hears an unfamiliar song from a bird of the same species, a zebra finch stops chirping, hopping and grooming. It listens attentively for minutes at a time, occasionally cocking its head but otherwise ...
Jun 30, 2011 |
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Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders
Blocking two tiny molecules of RNA – a chemical cousin of DNA – appears to suppress the abnormal growth of blood vessels that occurs in degenerative eye disorders, UT Southwestern Medical Center researchers have ...
Jun 07, 2011 |
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Tiny RNA molecule removal can inhibit cancer growth
Research from the University of Louisville published today (June 6) in the Proceedings of the National Academy of Sciences indicates the removal of a tiny RNA molecule in mice suppresses carcinogenic tumor formation. The st ...
Jun 06, 2011 |
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Scientists investigate possible key to non-invasive prostate testing
The project, led by Chancellor's Postdoctoral Research Fellow Dr. Nham Tran and Head of the Translational Cancer Research Group Dr. Rosetta Martiniello-Wilks, will establish if microRNA collected from body fluids can signal ...
Feb 17, 2011 |
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Researchers reveal function of novel molecule that underlies human deafness
New research from the University of Sheffield has revealed that the molecular mechanism underlying deafness is caused by a mutation of a specific microRNA called miR-96. The discovery could provide the basis for treating ...
Jan 21, 2011 |
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Discovery could shrink dengue-spreading mosquito population
Each year, dengue fever infects as many as 100 million people while yellow fever is responsible for about 30,000 deaths worldwide. Both diseases are spread by infected female Aedes aegypti mosquitoes, which ...
Dec 02, 2010 |
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MicroRNA
In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression. They were first described in 1993 by Lee and colleagues in the Victor Ambros lab , yet the term microRNA was only introduced in 2001 in a set of three articles in Science.
For more information about MicroRNA, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
