When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, ...
Cell & Microbiology
May 25, 2022
0
154
Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, Buck Institute scientists have discovered a new mechanism of how mitochondria start to go wrong, ...
Cell & Microbiology
May 19, 2022
0
53
Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED. TALEDs are base editors ...
Biotechnology
Apr 25, 2022
0
44
Defective mitochondria—the 'batteries' that power the cells of our bodies—could in future be repaired using gene-editing techniques. Scientists at the University of Cambridge have shown that it is possible to modify the ...
Biotechnology
Feb 8, 2022
0
158
Mutant DNA sequences inside cellular mitochondria can be eliminated using a bespoke chemical compound. The approach, developed by scientists at Kyoto University's Institute for Integrated Cell-Material Science (iCeMS) in ...
Cell & Microbiology
Aug 27, 2021
0
197
The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical ...
Biotechnology
Jul 15, 2021
0
16
In a study published in Nature Communications, researchers at Karolinska Institutet provide insight into the sequence of events leading to formation of functional mitoribosomes and sheds light on the mechanism of action of ...
Biotechnology
Jun 16, 2021
0
10
Mitochondria—the 'batteries' that power our cells—play an unexpected role in common diseases such as type 2 diabetes and multiple sclerosis, concludes a study of over 350,000 people conducted by the University of Cambridge.
Molecular & Computational biology
May 17, 2021
0
1487
In a study of yeast, Johns Hopkins Medicine researchers say they have found how a fatty compound called cardiolipin helps create cellular energy. The researchers say their findings will help shed light on conditions that ...
Cell & Microbiology
Jan 6, 2021
0
110
Insofar as variants for mitochondrial disease are supposed to be rare in the genome, don't think for even a minute that it can't happen to you. In fact, the closer one looks at the full mitonuclear genomes of normal folks, ...
